Mesitylene

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Names

[ CAS No. ]:
108-67-8

[ Name ]:
Mesitylene

[Synonym ]:
2,4,6-Me3-Ph
sym-trimethylbenzene
2,4,6-trimethylbenzene
3,5-Dimethyltoluene
UNII-887L18KQ6X
Fleet-X
Trimethylbenzene,1,3,5
Trimethylbenzol
1,3,5-Trimethyl benzene
Trimethylbenzene, 1,3,5-
Symmetrical trimethylbenzene
2,4,6-collidine
EINECS 203-604-4
MFCD00008538
Benzene, 1,3,5-trimethyl-
Mesitylene
Benzene,1,3,5-trimethyl
1,3,5-trimethylbenzene
1,3,5-Me3C6H3

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
166.7±20.0 °C at 760 mmHg

[ Melting Point ]:
-45 °C

[ Molecular Formula ]:
C9H12

[ Molecular Weight ]:
120.192

[ Flash Point ]:
44.4±0.0 °C

[ Exact Mass ]:
120.093903

[ LogP ]:
3.60

[ Vapour density ]:
4.1 (vs air)

[ Vapour Pressure ]:
2.3±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.501

[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
2.9 g/L (20 ºC)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OX6825000
CHEMICAL NAME :
Mesitylene
CAS REGISTRY NUMBER :
108-67-8
LAST UPDATED :
199710
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C9-H12
MOLECULAR WEIGHT :
120.21
WISWESSER LINE NOTATION :
1R C1 E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,34,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,34,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Human
DOSE/DURATION :
10 ppm
TOXIC EFFECTS :
Peripheral Nerve and Sensation - sensory change involving peripheral nerve Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi
REFERENCE :
ZUBEAQ Zeitschrift fuer Unfallmedizin und Berufskrankheiten. Revue de Medecine des Accidents et des Maladies Professionelles. (Verlag Berichthaus, Zwingliplatz 3, Postfach, CH-8022, Zurich, Switzerland) V.1- 1907- Volume(issue)/page/year: 49,265,1956
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
24 gm/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 44(5),15,1979
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1303 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 9,227,1954 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20 mg/m3/24H/17W-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes in urine composition Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - catalases
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 44(5),15,1979 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-DENMARK:TWA 25 ppm (120 mg/m3) JAN 1993 OEL-SWEDEN:TWA 25 ppm (120 mg/m3);STEL 35 ppm (170 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 25 ppm (125 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1998 No. of Facilities: 495 (estimated) No. of Industries: 4 No. of Occupations: 6 No. of Employees: 12997 (estimated) No. of Female Employees: 231 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310 + P330-P302 + P352 + P312-P370 + P378

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xi:Irritant;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R10;R37;R51/53

[ Safety Phrases ]:
S61-S45-S36/37-S16-S7

[ RIDADR ]:
UN 2325 3/PG 3

[ WGK Germany ]:
2

[ RTECS ]:
OX6825000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2902909090

Synthetic Route

Precursor & DownStream

Precursor

  • 2-Chlorotoluene
  • Mesitylboronic acid
  • Mesitonitrile
  • 2,4,6-Trimethylbromobenzene
  • Phenyl ethyl ketone
  • Iodo-2,4,6-trimethylbenzene
  • 2,4,6-trimethylbenzoic acid 2-pyridinylmethyl ester
  • Carbon dioxide
  • Acetone
  • 2,4,6-Trimethylbenzoyl chloride

DownStream

  • 2,4,6-trimethyl-3-nitrobenzoic acid
  • 2-Mesitylacetic acid
  • 2,4,6-Trimethylbromobenzene
  • 2,4-Dibromomesitylene
  • a-Bromomesitylene
  • 2-CHLOROMESITYLENE
  • Benzene,1,3,5-tribromo-2,4,6-trimethyl-
  • Trimesic acid
  • Isophthalic acid
  • Uvitic acid

Customs

[ HS Code ]: 2902909090

[ Summary ]:
2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

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Related Compounds

  • mesitylene-d12
  • mesitylene-HCl
  • nitromesitylene
  • ethylmesitylene
  • Mesitylene oxide
  • Dinitromesitylene
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 3-(2,3-Dimethoxyphenyl)piperidine
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • (R)-tert-butyl 3-(benzo[d]isothiazol-3-yl(methyl)amino)piperidine-1-carboxylate
  • tert-Butyl-DL-alanine