1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid

Names

[ CAS No. ]:
108138-27-8

[ Name ]:
1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid

[Synonym ]:
t 1814

Chemical & Physical Properties

[ Density]:
1.48g/cm3

[ Boiling Point ]:
611ºC at 760 mmHg

[ Molecular Formula ]:
C20H16F3N3O3

[ Molecular Weight ]:
403.35500

[ Flash Point ]:
323.3ºC

[ Exact Mass ]:
403.11400

[ PSA ]:
74.57000

[ LogP ]:
2.90960

[ Vapour Pressure ]:
8.74E-16mmHg at 25°C

[ Index of Refraction ]:
1.62

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Piperazine
  • 1-(2,4-DIFLUOROPHENYL)-6,7-DIFLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID
  • 2,4-Difluoroaniline
  • 2,4,5-Trifluorobenzoic acid
  • Ethyl 3-oxo-3-(2,4,5-trifluorophenyl)propanoate
  • 6,7-difluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid ethyl ester
  • ethyl 3-(2,4-difluoroanilino)-2-(2,4,5-trifluorobenzoyl)acrylate

DownStream