p-iodoclonidine hydrochloride

Names

[ Name ]:
p-iodoclonidine hydrochloride

[Synonym ]:
2-[(2,6-DICHLORO-4-IODOPHENYL)IMINO]IMIDAZOLINE HYDROCHLORIDE
p-iodoclinidine
4-iodoclonidine
p-iodoclonidineHCl
iodoclonidine
MFCD00069292

Chemical & Physical Properties

[ Density]:
2.08g/cm3

[ Boiling Point ]:
375.8ºC at 760mmHg

[ Molecular Formula ]:
C₉H₉Cl₃IN₃

[ Molecular Weight ]:
392.45100

[ Flash Point ]:
181.1ºC

[ Exact Mass ]:
390.89100

[ PSA ]:
36.42000

[ LogP ]:
4.23790

[ Appearance of Characters ]:
solid | white or off-white

[ Vapour Pressure ]:
7.59E-06mmHg at 25°C

[ Index of Refraction ]:
1.754

[ Water Solubility ]:
H2O: soluble

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933290090

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Imidazoline and alpha(2a)-adrenoceptor binding sites in postmenopausal women before and after estrogen replacement therapy.

Biol. Psychiatry 48(9) , 932-9, (2000)

Platelet alpha(2A)-adrenoceptors (alpha(2A)AR) and imidazoline binding sites (subtype I(1)) have been proposed as peripheral markers of brain stem receptors that mediate sympathetic outflow and are re...

Pharmacological characterization of [3H]idazoxan, [3H]RX821002 and p-[125I]iodoclonidine binding to alpha 2-adrenoceptors in rat cerebral cortical membranes.

Eur. J. Pharmacol. 258(1-2) , 67-76, (1994)

Binding characteristics of alpha 2-adrenoceptors in rat cerebral cortical membranes were compared using the antagonist radioligands [3H]idazoxan, [3H]2-(2-methoxy-1,4-benzodioxan-2-yl)-2-imidazoline (...

Catecholamines and angiotensinogen gene expression in kidney proximal tubular cells.

Mol. Cell Biochem. 212(1-2) , 73-9, (2000)

To investigate the molecular mechanism(s) of action of catecholamines on the expression of the angiotensinogen (ANG) gene in kidney proximal tubular cells, we used opossum kidney (OK) cells with a fus...

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