4-([tert-Butyl(dimethyl)silyl]oxy)phenol

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Names

[ CAS No. ]:
108534-47-0

[ Name ]:
4-([tert-Butyl(dimethyl)silyl]oxy)phenol

[Synonym ]:
Phenol, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-
MFCD06200713
4-([tert-Butyl(dimethyl)silyl]oxy)phenol
Phenol,4-t-butyldimethylsilyloxy
4-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}phenol

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
266.4±23.0 °C at 760 mmHg

[ Melting Point ]:
60-64ºC(lit.)

[ Molecular Formula ]:
C12H20O2Si

[ Molecular Weight ]:
224.372

[ Flash Point ]:
114.9±22.6 °C

[ Exact Mass ]:
224.123260

[ PSA ]:
29.46000

[ LogP ]:
-0.21

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.491

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R41

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • tert-Butyldimethylsilyl chloride
  • Hydroquinone
  • Imidazole
  • 4-Benzyloxyphenol
  • (3R,4R,5R)-5-hydroxy-3,4-(isopropylidenedioxy)-1-cyclohexanone
  • 4-((tert-butyldimethylsilyl)oxy)-4-methoxycyclohexa-2,5-dienone
  • 4-((tert-butyldimethylsilyl)oxy)-4-methoxycyclohexa-2,5-dienol

DownStream

Related Compounds

  • 4-[tert-butyl(dimethyl)silyl]oxy-2-methyl-3-phenylbut-2-en-1-ol
  • 4-[tert-butyl(dimethyl)silyl]oxy-2-methylbutan-1-ol
  • 4-[tert-butyl(dimethyl)silyl]oxy-4-oxobutanoic acid
  • 4-[tert-butyl(dimethyl)silyl]oxy-1-phenylbut-2-en-1-one
  • 4-[tert-butyl(dimethyl)silyl]oxy-2-iodobut-2-en-1-ol
  • 4-[tert-butyl(dimethyl)silyl]oxy-3-methoxybenzaldehyde
  • N-(3-methoxyphenyl)-7-methyl-4-oxo-4H-pyrido[1,2-a]thieno[2,3-d]pyrimidine-2-carboxamide
  • N-(2-methoxyphenyl)-7-methyl-4-oxo-4H-pyrido[1,2-a]thieno[2,3-d]pyrimidine-2-carboxamide
  • 12-methyl-2-oxo-N-(pyridin-3-yl)-6-thia-1,8-diazatricyclo[7.4.0.0^{3,7}]trideca-3(7),4,8,10,12-pentaene-5-carboxamide
  • N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-7-methyl-4-oxo-4H-pyrido[1,2-a]thieno[2,3-d]pyrimidine-2-carboxamide
  • 5-[4-(3-Chlorophenyl)piperazine-1-carbonyl]-12-methyl-6-thia-1,8-diazatricyclo[7.4.0.0^{3,7}]trideca-3(7),4,8,10,12-pentaen-2-one
  • 5-[4-(Furan-2-carbonyl)piperazine-1-carbonyl]-12-methyl-6-thia-1,8-diazatricyclo[7.4.0.0^{3,7}]trideca-3(7),4,8,10,12-pentaen-2-one
  • 7-methyl-4-oxo-N-(3-(2-oxopyrrolidin-1-yl)propyl)-4H-pyrido[1,2-a]thieno[2,3-d]pyrimidine-2-carboxamide
  • 7-methyl-4-oxo-N-(pyridin-2-ylmethyl)-4H-pyrido[1,2-a]thieno[2,3-d]pyrimidine-2-carboxamide
  • Ethyl 4-[3-(7-methyl-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)propanoyl]piperazine-1-carboxylate
  • 2-[3-(4-benzylpiperidin-1-yl)-3-oxopropyl]-7-methyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one
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