Dibenzyl diisopropylphosphoramidoite

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Names

[ CAS No. ]:
108549-23-1

[ Name ]:
Dibenzyl diisopropylphosphoramidoite

[Synonym ]:
MFCD00191988
Dibenzyl diisopropylphosphoramidoite
Dibenzyl diisopropylphosphoramidite
Phosphoramidous acid, bis(1-methylethyl)-, bis(phenylmethyl) ester
Dibenzyloxy(diisopropylamino)phosphine
N-bis(phenylmethoxy)phosphanyl-N-propan-2-ylpropan-2-amine
Dibenzyl N,N-Diisopropylphosphoramidite
Phosphoramidous acid, N,N-bis(1-methylethyl)-, bis(phenylmethyl) ester

Chemical & Physical Properties

[ Density]:
1.028 g/mL at 25 °C(lit.)

[ Boiling Point ]:
382.0±31.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H28NO2P

[ Molecular Weight ]:
345.42

[ Flash Point ]:
184.8±24.8 °C

[ Exact Mass ]:
345.185760

[ PSA ]:
35.29000

[ LogP ]:
6.82

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.535(lit.)

[ Storage condition ]:
Store at 0°C

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2931900090

Synthetic Route

Precursor & DownStream

Precursor

  • diisopropylphosphoramidous dichloride
  • Benzyl alcohol
  • Diisopropylamine
  • Benzyl N,N,N',N'-Tetraisopropylphosphorodiamidite
  • Benzyl chloroformate
  • BENZYL DICHLOROPHOSPHITE

DownStream

  • Boc-ethanolamine Dibenzylphosphate
  • dibenzyl phosphite
  • dibenzyl (2-(2,4-difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)propan-2-yl) phosphate
  • Dibenzyl phosphite
  • Dibenzyl phosphate
  • dibenzyl (biphenyl-4-yl 2,4,6-tri-O-benzoyl-α-D-mannopyranoside) 3-phosphate

Customs

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Articles

Therapeutic targeting of oncogenic K-Ras by a covalent catalytic site inhibitor.

Angew. Chem. Int. Ed. Engl. 53(1) , 199-204, (2014)

We report the synthesis of a GDP analogue, SML-8-73-1, and a prodrug derivative, SML-10-70-1, which are selective, direct-acting covalent inhibitors of the K-Ras G12C mutant relative to wild-type Ras....

Differential hormone-dependent phosphorylation of progesterone receptor A and B forms revealed by a phosphoserine site-specific monoclonal antibody.

Mol. Endocrinol. 14(1) , 52-65, (2000)

Human progesterone receptor (PR) is phosphorylated on multiple serine residues (at least seven sites) in a manner that involves distinct groups of sites coordinately regulated by hormone and different...

A new reaction for the direct conversion of 4-azido-4-deoxy-D-galactoside into a 4-deoxy-D-erythro-hexos-3-ulose.

Org. Lett. 6 , 1365-1368, (2004)

[reaction: see text] A new one-step reaction has been developed for converting 4-azido-4-deoxy-d-galactoside into 4-deoxy-d-erythro-hexos-3-ulose by phosphoramidites and tetrazole. It is proposed that...


More Articles


Related Compounds

  • dibenzyl octanedioate
  • Dibenzyl Phthalate-3,4,5,6-d4
  • dibenzyl phenylphosphonate
  • dibenzyl 4-oxoazetidine-1,2-dicarboxylate
  • dibenzyl hydrogen dithiophosphate
  • dibenzyl 3,3'-bis-(2-methoxycarbonylethyl)-4,4'-dimethyl-2,2'-methylenedipyrrole-5,5'-dicarboxylate
  • 4-Amino-4-(methanesulfonylmethyl)cyclohexan-1-ol
  • 3,6-Dichloro-4-isocyanatopyridazine
  • 1-(4-Bromo-2,3,5,6-tetramethylphenyl)propan-2-one
  • (3R)-3-hydroxy-3-(2,2,3,3-tetramethylcyclopropyl)propanoic acid
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-(3,3,3-trifluoropropanamido)acetate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 7-ethyl-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-{[(tert-butoxy)carbonyl]amino}-2-(3-methoxyphenyl)acetate
  • 2-(2,4-Dimethoxypyridin-3-yl)-2,2-difluoroacetic acid
  • 3-Chloro-2-(2-fluoro-1-hydroxyethyl)phenol
  • 5-(3-Bromopropyl)-6-methoxy-1,3-dioxaindane
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