Pyridin-3-ol

Suppliers

Names

[ CAS No. ]:
109-00-2

[ Name ]:
Pyridin-3-ol

[Synonym ]:
β-Hydroxypyridine
m-Hydroxypyridine
2-PYRIDON
3-Pyridinol
3-PYRIDOL
EINECS 205-520-3
T6NJ CQ
3-Pyridinol,3-Pyridone
3-HP
3-pyridinylphenol
pyridin-3-ol
B-PYRIDONE
3-Pyridyl alcohol
3-Oxopyridine
3-OH-pyridine
3-hydroxy-pyridine
3-PYRIDONE
MFCD00006268

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
318.9±0.0 °C at 760 mmHg

[ Melting Point ]:
125-128 °C(lit.)

[ Molecular Formula ]:
C5H5NO

[ Molecular Weight ]:
95.099

[ Flash Point ]:
146.6±20.4 °C

[ Exact Mass ]:
95.037117

[ PSA ]:
33.12000

[ LogP ]:
0.64

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.560

[ Storage condition ]:
Store at RT.

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UU7701400
CHEMICAL NAME :
3-Pyridinol
CAS REGISTRY NUMBER :
109-00-2
LAST UPDATED :
199709
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C5-H5-N-O
MOLECULAR WEIGHT :
95.11
WISWESSER LINE NOTATION :
T6NJ CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1822 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 23,815,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
900 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 16,259,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
UV1144050

[ HS Code ]:
29333999

Synthetic Route

Precursor & DownStream

Precursor

  • 3-Pyridinol 1-oxide
  • 3-Bromopyridine
  • 3-Chloropyridine
  • 3-Pyridylboronic acid
  • 3-acetoxypyridine
  • 3-Methoxypyridine
  • 3-Iodopyridine
  • 3-[(triisopropylsilyl)oxy]pyridine

DownStream

  • 2-(Trifluoromethyl)-3-pyridinol
  • 3-(2,2-dimethoxyethoxy)pyridine
  • 1-(2,4-dinitrophenyl)-3-methoxypyridin-1-ium,chloride
  • 6-Amino-3-pyridinol
  • 3-Fluoropyridine
  • 1-Methyl-3-piperidinol
  • 1-Methyl-3-piperidinone
  • Pyrazolo[1,5-a]pyridin-4-ol
  • 2,6-Pyridinedimethanol,3-hydroxy-, hydrochloride (1:1)
  • 4,5-Bis(3-pyridinyloxy)phthalonitrile

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Combination of Genistein and Cisplatin with Two Designed Monofunctional Platinum Agents in Human Ovarian Tumour Models.

Anticancer Res. 35 , 6027-39, (2015)

A great amount of research effort has been directed at platinum compounds that bind with DNA differently from cisplatin with the idea that the difference may translate into an altered spectrum of acti...

Preparative-scale isoelectric trapping by recursive electrophoresis in a compartmentalized system having orthogonal primary and secondary pH gradients. Part 2--operation in cascade mode.

Electrophoresis 32(20) , 2805-8, (2011)

A parallel multicompartmental electrolyzer recently developed for preparative-scale isoelectric trapping separations, trapping by recursive electrophoresis in a compartmentalized system, was set up to...

Preparative-scale isoelectric trapping by recursive electrophoresis in a compartmentalized system having orthogonal primary and secondary pH gradients. Part 1--construction and standard operation.

Electrophoresis 32(20) , 2797-804, (2011)

The performance of the current preparative-scale isoelectric trapping systems is limited by the serial arrangement of the separation compartments. A new system has been developed that achieves trappin...


More Articles


Related Compounds

  • 2-p-tolyl-pyridin-3-ol
  • 2-isobutylpyridin-3-ol
  • 2-Phenethyl-pyridin-3-ol
  • 6-Benzyloxy-pyridin-3-ol
  • Pyridin-3-ol,Hydrochlorid
  • Thieno[3,2-b]pyridin-3-ol
  • (S)-Fmoc-AAHA(Boc)-OH
  • 4-Amino-2-(ethoxymethyl)phenol
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 1-[2-(Methylsulfanyl)pyridine-3-carbonyl]-4-(3-phenylprop-2-en-1-yl)piperazine
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde