3-Dimethylaminopropylamine
Suppliers
Names
[ CAS No. ]:
109-55-7
        
[ Name ]:
 3-Dimethylaminopropylamine
        
[Synonym ]:
                
                EINECS 203-680-9
                
                
            
                
                DMPDA
                
                
            
                
                N1,N1-dimethylpropane-1,3-diamine
                
                
            
                
                N,N-Dimethyl-1,3-propanediamine
                
                
            
                
                3-(dimethylamino)-n-propylamine
                
                
            
                
                3-(Dimethylamino)propylamine
                
                
            
                
                N,N-dimethyl-1,3-diamino-propane
                
                
            
                
                FENTAMINE DMAPA
                
                
            
                
                N,N-dimethylamino-3-aminopropane
                
                
            
                
                U-CAT 2000
                
                
            
                
                3-(N,N-dimethylamino)prop-1-ylamine
                
                
            
                
                N,N-Dimethyl-1,3-propylenediamine
                
                
            
                
                RARECHEM AL BW 0072
                
                
            
                
                imethylaminopropylamine
                
                
            
                
                1-Amino-3-(dimethylamino)propane
                
                
            
                
                DMAPA
                
                
            
                
                N,N-dimethyl-propane-1,3-diamine
                
                
            
                
                N,N-Dimethyltrimethylenediamine
                
                
            
                
                H2N(CH2)3N(CH3)2
                
                
            
                
                γ-(Dimethylamino)propylamine
                
                
            
                
                3-aminopropyldimethylamine
                
                
            
                
                3-(Dimethylamino)-1-propylamine
                
                
            
                
                MFCD00008216
                
                
            
                
                (CH3)2N(CH2)3NH2
                
                
            
                
                N,N-Dimethyl-1,3-diaminopropane
                
                
            
                
                1,3-Propanediamine, N,N-dimethyl-
                
                
            
                
                3-(N,N-dimethylamino)propylamine
                
                
            
                
                DIMETHYLAMINOPROPYLAMINE
                
                
                
                
    
Chemical & Physical Properties
[ Density]:
0.81
            
[ Boiling Point ]:
133 ºC
            
[ Melting Point ]:
-60 °C
            
[ Molecular Formula ]:
C5H14N2
            
[ Molecular Weight ]:
102.178
            
[ Flash Point ]:
32 ºC
            
[ Exact Mass ]:
102.115700
            
[ PSA ]:
29.26000
            
[ LogP ]:
-0.29
            
[ Vapour density ]:
3.6 (vs air)
            
[ Vapour Pressure ]:
10.1±0.2 mmHg at 25°C
            
[ Index of Refraction ]:
1.434-1.436
            
[ Water Solubility ]:
SOLUBLE
            
[ Freezing Point ]:
-70℃
            
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
 - TX7525000
 
- CHEMICAL NAME :
 - 1,3-Propanediamine, N,N-dimethyl-
 
- CAS REGISTRY NUMBER :
 - 109-55-7
 
- BEILSTEIN REFERENCE NO. :
 - 0605293
 
- LAST UPDATED :
 - 199710
 
- DATA ITEMS CITED :
 - 10
 
- MOLECULAR FORMULA :
 - C5-H14-N2
 
- MOLECULAR WEIGHT :
 - 102.21
 
- WISWESSER LINE NOTATION :
 - Z3N1&1
 
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
 - Open irritation test
 
- ROUTE OF EXPOSURE :
 - Administration onto the skin
 
- SPECIES OBSERVED :
 - Rodent - rabbit
 
- REFERENCE :
 - AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
 
- TYPE OF TEST :
 - Standard Draize test
 
- ROUTE OF EXPOSURE :
 - Administration into the eye
 
- SPECIES OBSERVED :
 - Rodent - rabbit
 
- REFERENCE :
 - UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 12/15/1971 ** ACUTE TOXICITY DATA **
 
- TYPE OF TEST :
 - LD50 - Lethal dose, 50 percent kill
 
- ROUTE OF EXPOSURE :
 - Oral
 
- SPECIES OBSERVED :
 - Rodent - rat
 
- DOSE/DURATION :
 - 1870 mg/kg
 
- TOXIC EFFECTS :
 - Details of toxic effects not reported other than lethal dose value
 
- REFERENCE :
 - AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
 
- TYPE OF TEST :
 - LD50 - Lethal dose, 50 percent kill
 
- ROUTE OF EXPOSURE :
 - Administration onto the skin
 
- SPECIES OBSERVED :
 - Rodent - rabbit
 
- DOSE/DURATION :
 - 600 uL/kg
 
- TOXIC EFFECTS :
 - Details of toxic effects not reported other than lethal dose value
 
- REFERENCE :
 - UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 12/15/1971 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 2 mg/m3;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83852 No. of Facilities: 126 (estimated) No. of Industries: 5 No. of Occupations: 11 No. of Employees: 998 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83852 No. of Facilities: 124 (estimated) No. of Industries: 3 No. of Occupations: 7 No. of Employees: 6127 (estimated) No. of Female Employees: 119 (estimated)
 
Safety Information
[ Symbol ]:
                
                
                GHS02, GHS05, GHS07
            
[ Signal Word ]: 
Danger
            
[ Hazard Statements ]:
 H226-H302 + H312-H314-H317-H335
            
[ Precautionary Statements ]:
 P210-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P333 + P313-P403 + P235
            
[ Personal Protective Equipment ]:
 Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
            
[ Hazard Codes ]:
 C:Corrosive
            
[ Risk Phrases ]:
 R10;R22;R34;R43
            
[ Safety Phrases ]:
 S26-S36/37/39-S45
            
[ RIDADR ]: 
UN 2733 3/PG 3
            
[ WGK Germany ]: 
2
            
[ RTECS ]: 
T7525000
            
[ Packaging Group ]:
 II
            
[ Hazard Class ]:
8
            
[ HS Code ]:
 29212900
            
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921290000
[ Summary ]: 
2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
            
Articles
Am. J. Trop. Med. Hyg. 91(4) , 824-32, (2014)
Because of emerging resistance to existing drugs, new chemical classes of antimalarial drugs are urgently needed. We have rationally designed a library of compounds that were predicted to accumulate i...
J. Control. Release 152 Suppl 1 , e93-4, (2011)
Biochem. Soc. Trans. 22(3) , 308S, (1994)