β-Nicotinamide mononucleotide

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Names

[ CAS No. ]:
1094-61-7

[ Name ]:
β-Nicotinamide mononucleotide

[Synonym ]:
3-Carbamoyl-1-[5-O-(hydroxyphosphinato)-β-D-ribofuranosyl]pyridinium
MFCD00038748
Beta-Nicotinamide Mononucleotide
pyridinium, 3-(hydroxyiminomethyl)-1-(5-O-phosphono-β-D-ribofuranosyl)-, inner salt
Nicotinamide D-ribonucleotide
3-(Aminocarbonyl)-1-(5-O-phosphono-b-D-ribofuranosyl)pyridinium Hydroxide Inner Salt
NMN zwitterion
EINECS 214-136-5
β-nicotinamide mononucleotide
3-Carbamoyl-1-b-D-ribofuranosylpyridinium Hydroxide 5'-(Dihydrogen Phosphate) Inner Salt
Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)-, inner salt
[(2R,3S,4R,5R)-5-(3-Carbamoyl-1-pyridiniumyl)-3,4-dihydroxytetrahydro-2-furanyl]methyl hydrogen phosphate
beta-NMN
Nicotinamide ribonucleotide
NMN

Chemical & Physical Properties

[ Molecular Formula ]:
C11H15N2O8P

[ Molecular Weight ]:
334.219

[ Exact Mass ]:
334.056610

[ PSA ]:
176.06000

[ LogP ]:
-3.38

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Precursor & DownStream

Precursor

  • N1-(β-D-Ribofuranosyl)-3-aminocarbonylpyridinium bromide
  • NAD+
  • 1-(2,4-dinitrophenyl)pyridin-1-ium-3-carboxamide,chloride
  • ribose 5-phosphate bis(cyclohexylammonium) salt
  • phosphoribosylamine
  • N1-(2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl)-3-aminocarbonylpyridinium bromide
  • 3-carbamoyl-1-(tri-O-acetyl-α-D-ribofuranosyl)-pyridinium, bromide
  • b-D-Ribofuranose 1-acetate 2,3,5-tribenzoate

DownStream

  • NAD+
  • Nicotinamide

Articles

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J. Immunol. 195 , 4999-5010, (2015)

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A possibility of nutriceuticals as an anti-aging intervention: activation of sirtuins by promoting mammalian NAD biosynthesis.

Pharmacol. Res. 62(1) , 42-7, (2010)

Aging science has recently drawn much attention, and discussions on the possibility of anti-aging medicine have multiplied. One potential target for the development of anti-aging drugs is the SIR2 (si...

The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism.

Biochem. J. 441(1) , 131-41, (2012)

Haemophilus influenzae is a major pathogen of the respiratory tract in humans that has developed the capability to exploit host NAD(P) for its nicotinamide dinucleotide requirement. This strategy is o...


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Related Compounds

  • β-nicotinamide mononucleotide, reduced form, disodium salt
  • β-NICOTINAMIDE ADENINE DINUCLEOTIDE TETRAHYDRATE, CRYSTALLINE, 98+%
  • β-Nicotinamide adenine dinucleotide reduced dipotassium
  • ALPHA-NICOTINAMIDE MONONUCLEOTIDE
  • NMNH
  • Biotin-NAD+