2-[5-oxo-4-[2-oxo-2-(4-sulfamoylanilino)ethyl]-1,3-dioxolan-4-yl]acetic acid

Names

[ CAS No. ]:
109473-28-1

[ Name ]:
2-[5-oxo-4-[2-oxo-2-(4-sulfamoylanilino)ethyl]-1,3-dioxolan-4-yl]acetic acid

Chemical & Physical Properties

[ Density]:
1.589g/cm3

[ Molecular Formula ]:
C13H14N2O8S

[ Molecular Weight ]:
358.32400

[ Exact Mass ]:
358.04700

[ PSA ]:
170.47000

[ LogP ]:
1.26110

[ Index of Refraction ]:
1.614

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WM8070000
CHEMICAL NAME :
Succinic acid, 2-(hydroxymethoxy)-2-((p-sulfamoylphenylcarbamoyl)met hyl)-, gamma-lactone
CAS REGISTRY NUMBER :
109473-28-1
BEILSTEIN REFERENCE NO. :
0351694
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C13-H14-N2-O8-S
MOLECULAR WEIGHT :
358.35

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
570 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 47,853,1958

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • tert-Butyl 4-(ethyl(pyridin-2-ylmethyl)carbamoyl)piperidine-1-carboxylate
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide