Loratadine Impurity 19

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Names

[ CAS No. ]:
109537-11-3

[ Name ]:
Loratadine Impurity 19

[Synonym ]:
4-(9-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester
8-Dechloro-9-chloro Loratadine
Ethyl 4-(9-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxyate
Loratadine Impurity 19

Chemical & Physical Properties

[ Molecular Formula ]:
C22H23ClN2O2

[ Molecular Weight ]:
382.88300

[ Exact Mass ]:
382.14500

[ PSA ]:
42.43000

[ LogP ]:
4.82570

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethyl chloroformate
  • 9-chloro-11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine
  • N-tert-butyl-3-methylpyridine-2-carboxamide
  • 4-Chlorobenzyl chloride
  • magnesium,1-methylpiperidin-4-ide,chloride

DownStream

  • 8-Dechloro-9-chloro Desloratadine

Related Compounds

  • Desloratadine Impurity 19
  • Loratadine Impurity 24
  • Loratadine Impurity 3
  • Loratadine Impurity 23
  • Loratadine Impurity 14
  • Loratadine Impurity 25
  • Flunitrazepam H-3
  • [3H]Dofetilide
  • H5DU4Fds5M
  • TT9B5Gra2U
  • [8-(Propan-2-yl)-2-oxaspiro[4.5]decan-1-yl]methanesulfonyl chloride
  • 1-[(Pyrimidin-2-yl)methyl]cyclopropane-1-sulfonyl chloride
  • {8,8-Dimethyl-2-oxaspiro[4.5]decan-1-yl}methanesulfonyl chloride
  • 2-(3-Chloro-5-fluorophenyl)-2-fluoroethan-1-amine
  • benzyl N-[2-(chlorosulfonyl)ethyl]-N-[2-(2,2,2-trifluoroethoxy)ethyl]carbamate
  • benzyl N-[2-(chlorosulfonyl)-1-(4-fluorophenyl)ethyl]carbamate
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