Loratadine Impurity 19

Names

[ CAS No. ]:
109537-11-3

[ Name ]:
Loratadine Impurity 19

[Synonym ]:
4-(9-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester
8-Dechloro-9-chloro Loratadine
Ethyl 4-(9-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxyate
Loratadine Impurity 19

Chemical & Physical Properties

[ Molecular Formula ]:
C22H23ClN2O2

[ Molecular Weight ]:
382.88300

[ Exact Mass ]:
382.14500

[ PSA ]:
42.43000

[ LogP ]:
4.82570

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethyl chloroformate
  • 9-chloro-11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine
  • N-tert-butyl-3-methylpyridine-2-carboxamide
  • 4-Chlorobenzyl chloride
  • magnesium,1-methylpiperidin-4-ide,chloride

DownStream

  • 8-Dechloro-9-chloro Desloratadine

Related Compounds

  • Desloratadine Impurity 19
  • Loratadine Impurity 24
  • Loratadine Impurity 3
  • Loratadine Impurity 23
  • Loratadine Impurity 14
  • Loratadine Impurity 25