10-chloro-(20RS)-camptothecin

Names

[ CAS No. ]:
109581-98-8

[ Name ]:
10-chloro-(20RS)-camptothecin

[Synonym ]:
1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione,9-chloro-4-ethyl-4-hydroxy
10-Chloro-20(RS)-Camptothecin

Chemical & Physical Properties

[ Density]:
1.58g/cm3

[ Boiling Point ]:
776.5ºC at 760mmHg

[ Molecular Formula ]:
C20H15ClN2O4

[ Molecular Weight ]:
382.79700

[ Flash Point ]:
423.4ºC

[ Exact Mass ]:
382.07200

[ PSA ]:
81.42000

[ LogP ]:
2.73300

[ Vapour Pressure ]:
2.25E-25mmHg at 25°C

[ Index of Refraction ]:
1.75

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Amino-5-chlorobenzaldehyde
  • (±)- 1H-Pyrano[3,4-f]indolizine-3,6,10(4H)-trione, 4-ethyl-7,8-dihydro-4-hydroxy

DownStream

Related Compounds

  • 10-methyl-(20RS)-camptothecin
  • 10-aminocamptothecin
  • 10-chloro-6-methyl-2-propan-2-yl-2,6,9,11-tetrazabicyclo[5.4.0]undeca-7,9,11-trien-5-one
  • 10-chloro-dec-1-yne
  • 10-chloro-2-(3-furylmethyl)-6-methyl-2,6,9,11-tetrazabicyclo[5.4.0]undeca-7,9,11-trien-5-one
  • 10-chloro-2-(2-methoxyethyl)-6-methyl-2,6,9,11-tetrazabicyclo[5.4.0]undeca-7,9,11-trien-5-one