(s)-3-[[(1,1-dimethyl)dimethylsily]oxy]pentanedioic acid monomethyl ester

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Names

[ CAS No. ]:
109721-08-6

[ Name ]:
(s)-3-[[(1,1-dimethyl)dimethylsily]oxy]pentanedioic acid monomethyl ester

[Synonym ]:
3-t-butyldimethylsilanyloxy-1,5-pentanedioic acid monomethyl ester
hydroflumethyazide
Flutizide
Glomerulin
hydroflumenthiazide
Hidroflumetiazid
Spandiuril
Robezon
Saluron
Hydroflumethiazide
Diuredemina
Hidroalogen
Diurometon

Chemical & Physical Properties

[ Molecular Formula ]:
C12H24O5Si

[ Molecular Weight ]:
276.40100

[ Exact Mass ]:
276.13900

[ PSA ]:
72.83000

[ LogP ]:
2.41460

Safety Information

[ HS Code ]:
2931900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methanol
  • 3-(tert-butyldimethylsilyloxy)glutaric anhydride
  • (R)-1-methyl 5-((S)-1-phenylethyl) 3-((tert-butyldimethylsilyl)oxy)pentanedioate
  • (3S)-3-{[(tert-butyl)dimethylsilyl]oxy}-5-oxo-5-{[(1S)-1-phenylethyl]amino} pentanoic acid
  • Dimethyl 3-hydroxypentanedioate
  • dimethyl 3-acetyloxypentanedioate
  • tert-Butyldimethylsilyl chloride

DownStream

Customs

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%