(3R)-3-(tert-Butyldimethylsilyl)oxypentanedioate-1-methyl monoester

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Names

[ CAS No. ]:
109744-49-2

[ Name ]:
(3R)-3-(tert-Butyldimethylsilyl)oxypentanedioate-1-methyl monoester

[Synonym ]:
(3R)-3-[tert-butyl(dimethyl)silyl]oxy-5-methoxy-5-oxopentanoic acid
(3R)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid
(3R)-3-{[tert-Butyl(dimethyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid
Pentanedioic acid, 3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, monomethyl ester, (3R)-
(R)-3-(tert-Butyl-dimethyl-silanyloxy)-pentanedioicacidmonomethylester

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
327.4±32.0 °C at 760 mmHg

[ Molecular Formula ]:
C12H24O5Si

[ Molecular Weight ]:
276.401

[ Flash Point ]:
151.8±25.1 °C

[ Exact Mass ]:
276.139313

[ PSA ]:
72.83000

[ LogP ]:
3.27

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.447

Safety Information

[ HS Code ]:
2931900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methanol
  • 3-(tert-butyldimethylsilyloxy)glutaric anhydride
  • (3R)-3-(tert-Butyldimethylsilyloxy)glutaric acid-1-((R)-(-)-mandelic acid ester
  • hydrogen (3R)-1-methyl 3-[(tert-butyldimethylsilyl)-oxy]pentanedioate cyclohexylamine salt
  • Dimethyl 3-hydroxypentanedioate
  • dimethyl 3-acetyloxypentanedioate
  • tert-Butyldimethylsilyl chloride

DownStream

  • 5-Oxorosuvastatin Methyl Ester
  • Methyl (3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidenehexanoate

Customs

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • (Quinolin-2-yl)methyl sulfamate
  • Methyl 3-amino-2-(6-methoxy-1,3-dioxaindan-5-yl)propanoate
  • [3-(6-chloro-1H-indol-3-yl)-2,2-dimethylcyclopropyl]methanamine
  • 2-chloro-1-(2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-6-yl)ethan-1-one
  • 1-(2-Chloro-1,3-thiazol-5-yl)cyclopropane-1-carbaldehyde
  • 3-(5-Methyl-1,2-oxazol-4-yl)propanal
  • Methyl 4-(dimethylamino)-3-(1-hydroxyprop-2-en-1-yl)benzoate
  • 2-[1-(2-Hydroxy-5-methylphenyl)cyclopropyl]-2-methoxyacetic acid
  • O-[2-(3-ethyloxetan-3-yl)propyl]hydroxylamine
  • [(2-Methanesulfonylphenyl)methyl]hydrazine