(3R)-3-(tert-Butyldimethylsilyl)oxypentanedioate-1-methyl monoester

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Names

[ CAS No. ]:
109744-49-2

[ Name ]:
(3R)-3-(tert-Butyldimethylsilyl)oxypentanedioate-1-methyl monoester

[Synonym ]:
(3R)-3-[tert-butyl(dimethyl)silyl]oxy-5-methoxy-5-oxopentanoic acid
(3R)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid
(3R)-3-{[tert-Butyl(dimethyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid
Pentanedioic acid, 3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, monomethyl ester, (3R)-
(R)-3-(tert-Butyl-dimethyl-silanyloxy)-pentanedioicacidmonomethylester

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
327.4±32.0 °C at 760 mmHg

[ Molecular Formula ]:
C12H24O5Si

[ Molecular Weight ]:
276.401

[ Flash Point ]:
151.8±25.1 °C

[ Exact Mass ]:
276.139313

[ PSA ]:
72.83000

[ LogP ]:
3.27

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.447

Safety Information

[ HS Code ]:
2931900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methanol
  • 3-(tert-butyldimethylsilyloxy)glutaric anhydride
  • (3R)-3-(tert-Butyldimethylsilyloxy)glutaric acid-1-((R)-(-)-mandelic acid ester
  • hydrogen (3R)-1-methyl 3-[(tert-butyldimethylsilyl)-oxy]pentanedioate cyclohexylamine salt
  • Dimethyl 3-hydroxypentanedioate
  • dimethyl 3-acetyloxypentanedioate
  • tert-Butyldimethylsilyl chloride

DownStream

  • 5-Oxorosuvastatin Methyl Ester
  • Methyl (3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidenehexanoate

Customs

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • (2-Amino-6-methylpyridin-4-YL)boronic acid
  • 5-Cyclopropoxy-N2,N2,N3-trimethylpyridine-2,3-diamine
  • 4-Cyclopropoxy-5-(methylthio)-2-(trifluoromethyl)pyridine
  • 6-nitro-N-(pyrrolidin-3-yl)quinoxalin-2-amine hydrochloride
  • 6-nitro-N-(piperidin-4-yl)quinoxalin-2-amine hydrochloride
  • 1h-Pyrazolo[4,3-c]pyridine,5-acetyl-4,5,6,7-tetrahydro-3-phenyl-1-(phenylmethyl)-
  • N-cyclohexyl-2-fluoro-5-(trifluoromethyl)benzamide
  • 3-Ethyl-1-[2-(2-methyl-2,3-dihydroindol-1-yl)-2-oxoethyl]-4a,5,6,7,8,8a-hexahydroquinazoline-2,4-dione
  • 9-(3-methoxyphenyl)-1-methyl-3-phenacyl-6,7,8,9a,10,10a-hexahydro-4aH-purino[7,8-a]pyrimidine-2,4-dione
  • 6-(2,4-Dimethylphenoxy)nicotinaldehyde
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