Succinic acid

Suppliers

Names

[ CAS No. ]:
110-15-6

[ Name ]:
Succinic acid

[Synonym ]:
MFCD00002789
Butane diacid
Butanedioic acid,natural
HOOC-CH2-CH2-COOH
4-02-00-01908 (Beilstein Handbook Reference)
Bernsteinsaure [German]
Succinic acid
1,4-Butanedioic acid
1,2-Ethanedicarboxylic acid
Sal succini
QV2VQ
Succinic acid
Butanedioic acid
Asuccin
Katasuccin
Wormwood
EINECS 203-740-4
spirit of amber
AMBER ACID

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
236.1±13.0 °C at 760 mmHg

[ Melting Point ]:
185 °C

[ Molecular Formula ]:
C₄H₆O₄

[ Molecular Weight ]:
118.088

[ Flash Point ]:
110.9±16.3 °C

[ Exact Mass ]:
118.026611

[ PSA ]:
74.60000

[ LogP ]:
-0.59

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.478

[ Storage condition ]:
Store at RT.

[ Stability ]:
Stable. Substances to be avoided include strong bases, strong oxidizing agents. Combustible.

[ Water Solubility ]:
80 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WM4900000

CHEMICAL NAME :: Succinic acid

CAS REGISTRY NUMBER :: 110-15-6

BEILSTEIN REFERENCE NO. :: 1754069

LAST UPDATED :: 199701

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C4-H6-O4

MOLECULAR WEIGHT :: 118.10

WISWESSER LINE NOTATION :: QV2VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2260 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2702 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Human Fibroblast

DOSE/DURATION :: 20 mmol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 183,89,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84381 No. of Facilities: 316 (estimated) No. of Industries: 18 No. of Occupations: 21 No. of Employees: 3351 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84381 No. of Facilities: 1652 (estimated) No. of Industries: 16 No. of Occupations: 38 No. of Employees: 31198 (estimated) No. of Female Employees: 16182 (estimated)

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39-S37/39

[ RIDADR ]:
UN 3265 8/PG 3

[ WGK Germany ]:
1

[ RTECS ]:
WM4900000

[ Hazard Class ]:
8.0

[ HS Code ]:
2917190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

MALEIC ACID
Maleic acid
fumaric acid
Furfural
Maleic anhydride
Furan-2-carboxylic acid
5-hydroxymethylfurfural
Methanol
Butanoic acid,4-amino-4-oxo-
(±)-Malic Acid

DownStream

3-Hydroxyaspartic Acid
Glycine
methylamine
DL-Aspartic Acid
1,6,11,16-tetraoxacycloicosane-2,5,12,15-tetrone
meso-2,3-Dibromosuccinic acid
(±)-2,3-Dibromosuccinic acid
ditridecyl succinate
didecyl butanedioate
Succinohydrazide

Customs

[ HS Code ]: 2917190090

[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Urinary metabolic fingerprinting of mice with diet-induced metabolic derangements by parallel dual secondary column-dual detection two-dimensional comprehensive gas chromatography.

J. Chromatogr. A. 1361 , 265-76, (2014)

This study investigates the potential of a parallel dual secondary column-dual detection two-dimensional comprehensive GC platform (GC×2GC-MS/FID) for metabolic profiling and fingerprinting of mouse u...

Direct silylation of Trypanosoma brucei metabolites in aqueous samples and their GC-MS/MS analysis.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 967 , 134-8, (2014)

A simple two-step method for the derivatization of polar compounds (lactate, alanine, glycerol, succinate and glucose) using hexamethyldisilazane (HMDS) and N,O-bis(trimethylsilyl)trifluoroacetamide (...

Lactic acid production from acidogenic fermentation of fruit and vegetable wastes.

Bioresour. Technol. 191 , 53-8, (2015)

This work focused on the lactic acid production from acidogenic fermentation of fruit and vegetable wastes treatment. A long term completely stirred tank reactor (CSTR) lasting for 50 days was operate...