Isobutyl acetate

Suppliers

Names

[ CAS No. ]:
110-19-0

[ Name ]:
Isobutyl acetate

[Synonym ]:
Isobutyl ester of acetic acid
UNII-7CR47FO6LF
Isobutyl acetate
β -methylpropyl ethanoate
β-Methylpropyl ethanoate
Acetic Acid Isobutyl Ester
2-methylpropyl ethanoate
isobutyl ethanoate
MFCD00008932
2-methylpropyl acetate
iso-Butyl acetate
EINECS 203-745-1
Acetic acid, 2-methylpropyl ester

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
116.6±0.0 °C at 760 mmHg

[ Melting Point ]:
-99 °C

[ Molecular Formula ]:
C₆H₁₂O₂

[ Molecular Weight ]:
116.158

[ Flash Point ]:
21.7±0.0 °C

[ Exact Mass ]:
116.083733

[ PSA ]:
26.30000

[ LogP ]:
1.59

[ Vapour density ]:
>4 (vs air)

[ Vapour Pressure ]:
18.0±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.396

[ Water Solubility ]:
7 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AI4025000

CHEMICAL NAME :: Acetic acid, isobutyl ester

CAS REGISTRY NUMBER :: 110-19-0

BEILSTEIN REFERENCE NO. :: 1741909

LAST UPDATED :: 199712

DATA ITEMS CITED :: 31

MOLECULAR FORMULA :: C6-H12-O2

MOLECULAR WEIGHT :: 116.18

WISWESSER LINE NOTATION :: 1Y1&1OV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 11/3/1971

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,795,1978

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,795,1978 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 13400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 1,8,1974

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8000 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 4763 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IMSUAI Industrial Medicine and Surgery. (Northbrook, IL) V.18-42, 1949-73. For publisher information, see IOHSA5. Volume(issue)/page/year: 41,31,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >17400 mg/kg

REFERENCE :: NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 1,8,1974 *** REVIEWS *** ACGIH TLV-TWA 713 mg/m3 (150 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 150 ppm (700 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,139,1971 OSHA PEL (Gen Indu):8H TWA 150 ppm (700 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 150 ppm (700 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 150 ppm (700 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 150 ppm (700 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 150 ppm (700 mg/m3);STEL 187 ppm (875 mg/m3) JAN 1993 OEL-BELGIUM:TWA 150 ppm (713 mg/m3);STEL 187 ppm (888 mg/m3) JAN 1993 OEL-DENMARK:TWA 150 ppm (710 mg/m3) JAN 1993 OEL-FRANCE:TWA 150 ppm (710 mg/m3);STEL 200 ppm (940 mg/m3) JAN 1993 OEL-GERMANY:TWA 200 ppm (950 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 150 ppm (700 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 150 ppm (700 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 150 ppm (700 mg/m3);STEL 300 ppm JAN 1993 OEL-UNITED KINGDOM:TWA 150 ppm (700 mg/m3);STEL 187 ppm JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO ISOBUTYL ACETATE-air:10H TWA 150 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 40410 No. of Facilities: 16707 (estimated) No. of Industries: 150 No. of Occupations: 81 No. of Employees: 85472 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 40410 No. of Facilities: 11899 (estimated) No. of Industries: 113 No. of Occupations: 78 No. of Employees: 160286 (estimated) No. of Female Employees: 41243 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H336

[ Supplemental HS ]:
Repeated exposure may cause skin dryness or cracking.

[ Precautionary Statements ]:
P210-P370 + P378-P403 + P235

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F

[ Risk Phrases ]:
R11;R66

[ Safety Phrases ]:
S16-S23-S25-S29-S33

[ RIDADR ]:
UN 1213 3/PG 2

[ WGK Germany ]:
1

[ RTECS ]:
AI4025000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2915390090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-Methyl-2-propen-1-yl acetate
carbon monoxide
acetic acid,cyclopropylmethanol
isobutanol
Ethanoic anhydride
Acetyl chloride
ISOBUTYL VINYL ETHER
Methyl N-acetyl-L-phenylalaninate
4-Methyl-2-pentanone
propene

DownStream

Silicon tetraacetate
Benzyl acetate
isobutanol
acetic acid
Carbon dioxide
Acetone
Isobutylene
4-Methylbenzyl acetate
Riboflavine
Isobutyl 3-oxobutanoate

Customs

[ HS Code ]: 2915390090

[ Summary ]:
2915390090. esters of acetic acid. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:5.5%. General tariff:30.0%

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