trans-1,4-Dichlorobutene

Suppliers

Names

[ CAS No. ]:
110-57-6

[ Name ]:
trans-1,4-Dichlorobutene

[Synonym ]:
2-Butene, 1,4-dichloro-, (E)-
Toluene,2,5-dichloro
trans-1,4-Dichlorobutene
(2E)-1,4-Dichloro-2-butene
1,4-Dichloro-2-butene
Benzene,1,4-dichloro-2-methyl
trans 1,4-Dichloro-2-butene
(E)-1,4-Dichloro-2-butene
EINECS 203-779-7
TRANS-1,4-DICHLORO-2-BUTYLENE
2,5-dichloro-toluene
2,5-Dichlor-toluol
1,4-dichloro-toluene
MFCD00000988
TRANS-1,4-DICHLOROBUT-2-ENE
4-01-00-00787 (Beilstein Handbook Reference)
2-Butene, 1,4-dichloro-, (2E)-
(2E)-1,4-dichlorobut-2-ene
but-2-ene, trans-1,4-dichloro-
Toluene,5-dichloro
1,4-dichloro-2-methyl-benzene
TRANS-1,4-DICHLOR-2-BUTENE
1,4-Dichloro-trans-2-butene
2-Butene, 1,4-dichloro-, trans-
trans-1,4-Dichloro-2-butene

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
155.5±0.0 °C at 760 mmHg

[ Melting Point ]:
1-3ºC(lit.)

[ Molecular Formula ]:
C4H6Cl2

[ Molecular Weight ]:
124.996

[ Flash Point ]:
54.4±0.0 °C

[ Exact Mass ]:
123.984657

[ LogP ]:
1.97

[ Vapour Pressure ]:
3.9±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.459

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EM4903000
CHEMICAL NAME :
2-Butene, 1,4-dichloro-, (E)-
CAS REGISTRY NUMBER :
110-57-6
BEILSTEIN REFERENCE NO. :
1719693
LAST UPDATED :
199712
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C4-H6-Cl2
MOLECULAR WEIGHT :
125.00
WISWESSER LINE NOTATION :
G2U2G -T

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
86 ppm/4H
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Lungs, Thorax, or Respiration - other changes Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
AIHAM* Annual Meeting of American Industrial Hygiene Association. (Akron, OH) For publisher information, see AIHAAP. Volume(issue)/page/year: -,-,1968 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg/77W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg/77W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,149,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,149,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H301-H312-H314-H330

[ Precautionary Statements ]:
P260-P280-P284-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T+,T,F,N

[ Risk Phrases ]:
R10

[ Safety Phrases ]:
53-23-26-36/37/39-45-36/37-99-61-60

[ RIDADR ]:
UN 3390 6.1/PG 1

[ WGK Germany ]:
3

[ RTECS ]:
EM4903000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(a)

[ HS Code ]:
2903299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • butadiene
  • 3,4-dichlorobut-1-ene
  • (2Z)-1,4-Dichloro-2-butene
  • Methanol
  • 1,4-Dichlorobut-2-ene

DownStream

  • (E)-N,N,N',N'-tetramethylbut-2-ene-1,4-diamine
  • Phosphonic acid,2-butene-1,4-diylbis-, tetraethyl ester (9CI)
  • 2-Butene-1,4-diamine,N1,N1,N4,N4-tetraethyl-, (2E)-
  • 3-butene-1,2-diol
  • 2-BUTENE-1,4-DIOL
  • N,N'-dibutylbutane-1,4-diamine
  • 2-butene
  • 1-buten-3-yne
  • 2-ethenylspiro[2.4]hepta-4,6-diene
  • DL-1,4-Dichloro-2,3-butanediol

Customs

[ HS Code ]: 2903299090

[ Summary ]:
2903299090 other unsaturated chlorinated derivatives of acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity.

Bioorg. Med. Chem. 16 , 5720-32, (2008)

The risk of the presence of haloacetic acids in drinking water as chlorination by-products and the shortage of experimental mutagenicity data for most of them requires a research work. This paper desc...

Synthesis and biological properties of 9-(trans-4-hydroxy-2-buten-1-yl)adenine and guanine: open-chain analogues of neplanocin A.

J. Med. Chem. 30(2) , 437-40, (1987)

Alkylation of adenine (5a) or 2-amino-6-chloropurine (5b) with excess trans-1,4-dichloro-2-butene (4), effected by K2CO3 in dimethyl sulfoxide or tetra-n-butylammonium fluoride in tetrahydrofuran, led...

Effect of isomers of swainsonine on glycosidase activity and glycoprotein processing.

Biochemistry 26(9) , 2502-10, (1987)

The chemical synthesis of swainsonine [(1S,2R,8R,8 alpha R)-trihydroxyindolizidine] from trans-1,4-dichloro-2-butene was previously described [Adams, C. E., Walker, F. J., & Sharpless, K. B. (1985) J....


More Articles

Related Compounds

  • trans-1,4-dimethoxy-2-butene
  • trans-1,4-bis<(4'-methyl-2,2'-bipyridyl-4-yl)methyl>cyclohexane-1,4-diol
  • trans-1,4-Diethynylcyclohexane-1,4-diol
  • trans-1,4,4a,7,8,8a-hexahydro-2-(2-indol-3-ylethyl)-3(2H)-isoquinolone
  • trans-1-(4-isopropylcyclohexyl)piperidin-4-one
  • trans-1,4-dichlorocyclohexane
  • Ethyl 1-(2-(5-(2-fluorophenyl)isoxazol-3-yl)acetyl)piperidine-4-carboxylate
  • 2-(5-(2-fluorophenyl)isoxazol-3-yl)-N-(3-morpholinopropyl)acetamide
  • N-(3-(1H-imidazol-1-yl)propyl)-2-(5-(2-fluorophenyl)isoxazol-3-yl)acetamide
  • N-(benzo[d][1,3]dioxol-5-ylmethyl)-2-(5-(2-fluorophenyl)isoxazol-3-yl)acetamide
  • 2-(5-(2-fluorophenyl)isoxazol-3-yl)-N-(furan-2-ylmethyl)acetamide
  • 2-(5-(2-fluorophenyl)isoxazol-3-yl)-N-phenethylacetamide
  • N-(benzo[d][1,3]dioxol-5-yl)-2-(5-(2-fluorophenyl)isoxazol-3-yl)acetamide
  • N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-(5-(2-fluorophenyl)isoxazol-3-yl)acetamide
  • 2-(5-(2-fluorophenyl)isoxazol-3-yl)-N-(3-methylpyridin-2-yl)acetamide
  • 2-(5-(2-fluorophenyl)isoxazol-3-yl)-N-(5-methylisoxazol-3-yl)acetamide
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.