Calpain Inhibitor I

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Names

[ CAS No. ]:
110044-82-1

[ Name ]:
Calpain Inhibitor I

[Synonym ]:
N-Acetyl-L-leucyl-N-[(2S)-1-oxohexan-2-yl]-L-leucinamide
ALLN Ac-LLnL-CHO MG-101 N-Acetyl-Leu-Leu-Norleu-al N-Acetyl-L-leucyl-L-leucyl-L-norleucinal
Ac-Leu-Leu-Nle-H
AC-LL-NORLEUCINAL
AC-LEU-LEU-NORLEUCINAL
Ac-Leu-Leu-Nle-al
Calpain Inhibitor I,ALLN
CALPAIN INHIBITOR I
MG 101
ALLN
N-Acetyl-L-leucyl-N-((1S)-1-formylpentyl)-L-leucinamide
ac-llnl-cho
AC-LEU-LEU-NLE-CHO
acetylleucyl-leucyl-norleucinal
N-Acetyl-L-leucyl-N-[(2S)-1-oxo-2-hexanyl]-L-leucinamide
L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-1-formylpentyl]-
LLNL
CALPAIN INHIBITOR
MFCD00065505

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
632.2±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H37N3O4

[ Molecular Weight ]:
383.526

[ Flash Point ]:
192.9±30.3 °C

[ Exact Mass ]:
383.278412

[ PSA ]:
104.37000

[ LogP ]:
3.37

[ Appearance of Characters ]:
powder | white

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.474

[ Storage condition ]:
−20°C

[ Water Solubility ]:
DMSO: soluble | Soluble in dimethyl sulfoxide, ethanol, methanol. Insoluble in water, and aqueous buffers.

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Hook proteins: association with Alzheimer pathology and regulatory role of hook3 in amyloid beta generation.

PLoS ONE 10(3) , e0119423, (2015)

Defects in intracellular transport are implicated in the pathogenesis of Alzheimer's disease (AD). Hook proteins are a family of cytoplasmic linker proteins that participate in endosomal transport. In...

The role of proteases in excitation-contraction coupling failure in muscular dystrophy.

Am. J. Physiol. Cell Physiol. 308(1) , C33-40, (2015)

Duchenne muscular dystrophy (DMD) is one of the most frequent types of muscular dystrophy. Alterations in intracellular calcium (Ca(2+)) handling are thought to contribute to the disease severity in D...

Necrosis- and apoptosis-related Met cleavages have divergent functional consequences.

Cell Death Dis. 6 , e1769, (2015)

Upon activation by its ligand hepatocyte growth factor/scatter factor, the receptor tyrosine kinase Met promotes survival, proliferation, and migration of epithelial cells during embryogenesis. Deregu...


More Articles


Related Compounds

  • CALPAIN INHIBITOR I
  • Calpain Inhibitor IV
  • Calpain inhibitor II
  • calpain inhibitor ii
  • Calpain Inhibitor III
  • Calpain Inhibitor VI
  • 2-Methyl-6-{3-[(2-methylpyridin-4-yl)oxy]azetidine-1-carbonyl}-2,3-dihydropyridazin-3-one
  • 1,1-Difluoro-2-(3-methylthiophen-2-yl)propan-2-amine
  • 6-Fluoro-4-[4-(morpholine-4-carbonyl)piperidin-1-yl]quinazoline
  • 2-Methyl-3-[3-(morpholine-4-carbonyl)pyrrolidin-1-yl]quinoxaline
  • 4-[3-(4,4-Difluoropiperidine-1-carbonyl)pyrrolidin-1-yl]quinazoline
  • 2-[3-(4,4-Difluoropiperidine-1-carbonyl)pyrrolidin-1-yl]quinoxaline
  • N-[1-(1-methyl-1H-1,3-benzodiazol-2-yl)piperidin-4-yl]methanesulfonamide
  • 1-Cyclopropanecarbonyl-4-{[4-(trifluoromethoxy)phenyl]methyl}-1,4-diazepane
  • 4-{1-[(4-Chlorophenyl)methyl]piperidine-4-carbonyl}thiomorpholine
  • 1-(5-Cyclopropyl-1,3,4-thiadiazol-2-yl)-4-methanesulfonyl-1,4-diazepane
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