Indoximod

Suppliers

Names

[ Name ]:
Indoximod

[Synonym ]:
(2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid
D-Tryptophan, 1-methyl-
MFCD00274271
(2R)-2-amino-3-(1-methylindol-3-yl)propanoic acid
(R)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid
Indoximod
D-1MT
1-Methyl-D-tryptophan
NLG-8189

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
429.3±35.0 °C at 760 mmHg

[ Melting Point ]:
242-245 â„ƒ(lit.)

[ Molecular Formula ]:
C₁₂H₁₄N₂O₂

[ Molecular Weight ]:
218.252

[ Flash Point ]:
213.4±25.9 °C

[ Exact Mass ]:
218.105530

[ PSA ]:
68.25000

[ LogP ]:
1.43

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.625

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Tumor indoleamine 2,3-dioxygenase (IDO) inhibits CD19-CAR T cells and is downregulated by lymphodepleting drugs.

Blood 125 , 3905-16, (2015)

Although T cells expressing CD19-specific chimeric antigen receptors (CARs) are a promising new therapy for B-cell malignancies, objective responses are observed at lower frequencies in patients with ...

Rational design of indoleamine 2,3-dioxygenase inhibitors.

J. Med. Chem. 53 , 1172-89, (2010)

Indoleamine 2,3-dioxygenase (IDO) is an important therapeutic target for the treatment of diseases such as cancer that involve pathological immune escape. We have used the evolutionary docking algorit...

Amino acid metabolism inhibits antibody-driven kidney injury by inducing autophagy.

J. Immunol. 194 , 5713-24, (2015)

Inflammatory kidney disease is a major clinical problem that can result in end-stage renal failure. In this article, we show that Ab-mediated inflammatory kidney injury and renal disease in a mouse ne...

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(Rac)-Indoximod
(S)-Indoximod-d3
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