Salermide

Names

[ Name ]:
Salermide

[Synonym ]:
N-(3-{(E)-[(2-Hydroxy-1-naphthyl)methylene]amino}phenyl)-2-phenylpropanamide
Salermide
Benzeneacetamide, N-[3-[[(1E)-(2-hydroxy-1-naphthalenyl)methylene]amino]phenyl]-α-methyl-

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
666.7±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₆H₂₂N₂O₂

[ Molecular Weight ]:
394.465

[ Flash Point ]:
357.0±30.1 °C

[ Exact Mass ]:
394.168121

[ PSA ]:
61.69000

[ LogP ]:
5.40

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.623

[ Storage condition ]:
-20℃

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H317-H412

[ Precautionary Statements ]:
P273-P280

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts.

Biochim. Biophys. Acta 1850(2) , 401-10, (2015)

Psammaplin A (PsA) is a natural product isolated from marine sponges, which has been demonstrated to have anticancer activity against several human cancer cell lines via the induction of cell cycle ar...

Antiasthmatic effects of resveratrol in ovalbumin-induced asthma model mice involved in the upregulation of PTEN.

Biol. Pharm. Bull. 38(4) , 507-13, (2015)

Resveratrol, a natural polyphenolic compound known for its antioxidative and antiinflammatory effects, exerts antiasthmatic effects, although the mechanism underlying these effects remains elusive. Th...

A small molecule Inauhzin inhibits SIRT1 activity and suppresses tumour growth through activation of p53.

EMBO Mol. Med. 4(4) , 298-312, (2012)

Although ∼50% of all types of human cancers harbour wild-type TP53, this p53 tumour suppressor is often deactivated through a concerted action by its abnormally elevated suppressors, MDM2, MDMX or SIR...