ethyl (S)-2-[N-tosyl-(R)-prolyloxy]-2-[6-(acetylaminomethyl)-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate

Names

[ CAS No. ]:
110714-45-9

[ Name ]:
ethyl (S)-2-[N-tosyl-(R)-prolyloxy]-2-[6-(acetylaminomethyl)-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate

[Synonym ]:
.ethyl (S)-2-(N-tosyl-(R)-prolyloxy)-2-[6-(acetylaminomethyl)-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate
Ethyl (S)-6-(acetylaminomethyl)-

Chemical & Physical Properties

[ Molecular Formula ]:
C31H39N3O10S

[ Molecular Weight ]:
645.72000

[ Exact Mass ]:
645.23600

[ PSA ]:
167.92000

[ LogP ]:
3.37060

Synthetic Route

Precursor & DownStream

Precursor

  • ethyl bromo-[6-cyano-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl] acetate
  • ethyl 2-[N-tosyl-(R)-prolyloxy]-2-[6-cyano-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]acetate

DownStream

  • Campathecin
  • (S)-4-ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
  • ethyl (S)-2-[N-tosyl-(R)-prolyloxy]-2-[6-(acetoxymethyl)-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate

Related Compounds

  • 3-(Difluoromethyl)-5-iodopyridin-2-ol
  • 4-(Hydroxyamino)-5-methyl-5-phenyloxazol-2(5H)-one
  • (1r)-1-(4,6-Dichloropyridin-3-yl)ethan-1-amine
  • 3-Bromo-4-fluoro-2-nitrotoluene
  • 3-{[(Benzyloxy)carbonyl](2-methoxyethyl)amino}propanoic acid
  • 1-[(3-Methylphenyl)methyl]-4-phenyl-5-(2-phenylethynyl)-1H-1,2,3-triazole
  • {2-Oxaspiro[4.5]decan-3-yl}methanesulfonyl chloride
  • 2-(Pyrimidin-5-yl)ethane-1-thiol
  • (But-3-yn-2-yl)[(4-chloro-3-methylphenyl)methyl]amine
  • (R)-2-(3-Chloro-2-methylphenyl)-2-(methylamino)ethan-1-ol
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