ethyl (S)-2-[N-tosyl-(R)-prolyloxy]-2-[6-(acetoxymethyl)-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate

Names

[ CAS No. ]:
110714-46-0

[ Name ]:
ethyl (S)-2-[N-tosyl-(R)-prolyloxy]-2-[6-(acetoxymethyl)-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate

[Synonym ]:
.ethyl (S)-2-(N-tosyl-(R)-prolyloxy)-2-[6-(acetoxymethyl)-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate
Ethyl (S)-6-(acetoxymethyl)-

Chemical & Physical Properties

[ Molecular Formula ]:
C31H38N2O11S

[ Molecular Weight ]:
646.70500

[ Exact Mass ]:
646.22000

[ PSA ]:
165.12000

[ LogP ]:
3.40670

Synthetic Route

Precursor & DownStream

Precursor

  • ethyl bromo-[6-cyano-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl] acetate
  • ethyl 2-[N-tosyl-(R)-prolyloxy]-2-[6-cyano-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]acetate
  • ethyl (S)-2-[N-tosyl-(R)-prolyloxy]-2-[6-cyano-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate
  • ethyl (S)-2-[N-tosyl-(R)-prolyloxy]-2-[6-(acetylaminomethyl)-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate

DownStream

  • Campathecin
  • (S)-4-ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione

Related Compounds

  • 1-(3,5-Dichlorophenyl)-3,3,3-trifluoro-2,2-dihydroxypropan-1-one
  • (1R)-2,2,2-trifluoro-1-(1H-indol-4-yl)ethan-1-ol
  • 5-hydroxy-3-methyl-1-(pyridin-2-yl)-1H-pyrazole-4-carbonitrile
  • Tert-butyl 3-(2-chloro-6-fluorophenyl)piperazine-1-carboxylate
  • 5-(2-Isocyanatoethyl)-1,3-thiazole
  • 1-[(4-chloro-2-methoxypyridin-3-yl)methyl]-N-methylcyclopropan-1-amine
  • 4-(5-fluorofuran-2-yl)-N-methylaniline
  • 1-[1-(5-Bromopyridin-2-yl)cyclopropyl]cyclopropan-1-amine
  • 2-(2-Chloro-6-methoxyphenyl)-3-methylbutanoic acid
  • 2-(2-Bromo-6-methoxyphenyl)cyclopropan-1-amine
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