ethyl (S)-2-[N-tosyl-(R)-prolyloxy]-2-[6-(acetoxymethyl)-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate

Names

[ CAS No. ]:
110714-46-0

[ Name ]:
ethyl (S)-2-[N-tosyl-(R)-prolyloxy]-2-[6-(acetoxymethyl)-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate

[Synonym ]:
.ethyl (S)-2-(N-tosyl-(R)-prolyloxy)-2-[6-(acetoxymethyl)-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate
Ethyl (S)-6-(acetoxymethyl)-

Chemical & Physical Properties

[ Molecular Formula ]:
C31H38N2O11S

[ Molecular Weight ]:
646.70500

[ Exact Mass ]:
646.22000

[ PSA ]:
165.12000

[ LogP ]:
3.40670

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ethyl bromo-[6-cyano-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl] acetate
  • ethyl 2-[N-tosyl-(R)-prolyloxy]-2-[6-cyano-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]acetate
  • ethyl (S)-2-[N-tosyl-(R)-prolyloxy]-2-[6-cyano-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate
  • ethyl (S)-2-[N-tosyl-(R)-prolyloxy]-2-[6-(acetylaminomethyl)-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate

DownStream

  • Campathecin
  • (S)-4-ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione

Related Compounds

  • tert-butyl N-{1-oxo-2-[1-(propan-2-yl)-1H-pyrazol-5-yl]propan-2-yl}carbamate
  • [3,3-Difluoro-1-(2-phenylpropan-2-yl)cyclobutyl]methanamine
  • 3-fluoro-3-(1-methyl-1H-indol-3-yl)propan-1-amine
  • tert-butyl N-[2-(4-fluoro-2-methoxyphenyl)-1-oxopropan-2-yl]carbamate
  • {3-[3-(Difluoromethoxy)-4-methylphenyl]-2,2-dimethylcyclopropyl}methanamine
  • 2-Methyl-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]propan-1-amine
  • 2-(5-Phenylthiophen-2-yl)propanal
  • rac-(1R,2R)-2-(1H-indol-2-yl)cyclopropan-1-amine
  • rac-[(1R,2R)-2-{1H,4H,5H,6H-cyclopenta[c]pyrazol-3-yl}cyclopropyl]methanamine
  • 4-(1-amino-2-methoxypropan-2-yl)-N,N-dimethylbenzamide
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