ethyl (S)-2-[N-tosyl-(R)-prolyloxy]-2-[6-cyano-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate

Names

[ CAS No. ]:
110742-81-9

[ Name ]:
ethyl (S)-2-[N-tosyl-(R)-prolyloxy]-2-[6-cyano-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate

[Synonym ]:
Ethyl (S)-6-cyano-

Chemical & Physical Properties

[ Molecular Formula ]:
C29H33N3O9S

[ Molecular Weight ]:
599.65200

[ Exact Mass ]:
599.19400

[ PSA ]:
162.61000

[ LogP ]:
3.21528

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ethyl bromo-[6-cyano-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl] acetate

DownStream

  • Campathecin
  • (S)-4-ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
  • (4'S)-4'-ethyl-1',4',7',8'-tetrahydro-4'-hydroxy-3'H,10'H-spiro[1,3-dioxolane-2,6'-pyrano[3,4-f]indolizine]-3',10'-dione
  • ethyl (S)-2-[N-tosyl-(R)-prolyloxy]-2-[6-(acetoxymethyl)-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate

Related Compounds

  • 1-(4,6-Difluoro-1,3-benzothiazol-2-yl)pyrrolidine-2-carboxamide
  • 6-[5-(5-Cyanopyridin-2-yl)-octahydropyrrolo[3,4-b]pyrrol-1-yl]pyridine-2-carbonitrile
  • N,N-dimethyl-2-{4-[(pyridin-3-yl)methyl]piperazin-1-yl}pyrimidin-4-amine
  • N,N-dimethyl-4-{4-[(pyridin-3-yl)methyl]piperazin-1-yl}pyrimidin-2-amine
  • N,N-dimethyl-2-{4-[(pyridin-4-yl)methyl]piperazin-1-yl}pyrimidin-4-amine
  • 1-[7-(Trifluoromethyl)quinolin-4-yl]piperidin-4-ol
  • N-methyl-N-{1-[2-(1H-pyrazol-1-yl)ethyl]piperidin-3-yl}-3-(trifluoromethyl)pyridin-2-amine
  • 4-(4-{[(3-Chloropyridin-4-yl)oxy]methyl}piperidin-1-yl)-6-(trifluoromethyl)pyrimidine
  • 1-(4-Methoxy-7-methyl-1,3-benzothiazol-2-yl)pyrrolidine-2-carboxamide
  • 1-(6-Bromoquinazolin-4-yl)pyrrolidine-2-carboxamide