Bongkrekic acid

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Names

[ CAS No. ]:
11076-19-0

[ Name ]:
Bongkrekic acid

[Synonym ]:
Bongkrekic Acid, Triammonium Salt
BONGKREKIC ACID
Bongkrekic acid solution

Chemical & Physical Properties

[ Density]:
1.114g/cm3

[ Boiling Point ]:
715.1ºC at 760mmHg

[ Melting Point ]:
50-60°

[ Molecular Formula ]:
C28H38O7

[ Molecular Weight ]:
486.59700

[ Flash Point ]:
231ºC

[ Exact Mass ]:
486.26200

[ PSA ]:
121.13000

[ LogP ]:
5.88560

[ Appearance of Characters ]:
Lyophilized solid

[ Index of Refraction ]:
1.545

[ Storage condition ]:
-20°C

[ Water Solubility ]:
Soluble in DMSO (up to 100 mg/ml) or in Water (up to 1 mg/ml).

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JR1230000
CHEMICAL NAME :
2,4,8,10,14,18,20-Docosaheptaenedioic acid, 20-(carboxymethyl)-6-methoxy-2,5,17-trimethyl-, (R-(R*,S*(E,Z,Z,E,E,Z,E)))-
CAS REGISTRY NUMBER :
11076-19-0
LAST UPDATED :
199707
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C28-H38-O7
MOLECULAR WEIGHT :
486.66
WISWESSER LINE NOTATION :
QVY1&U2UY1&YO1&2U2U4U2Y1&1U1Y1VQU1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1410 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TETRAB Tetrahedron. (Pergamon Press Inc., Maxwell House, Fairview Park, Elm sford, NY 10523) V.1- 1957- Volume(issue)/page/year: 26,5993,1970

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ RIDADR ]:
NONH for all modes of transport

Articles

Changes in mitochondrial membrane potential during staurosporine-induced apoptosis in Jurkat cells.

FEBS Lett. 475 , 267, (2000)

Cytochrome c release from mitochondria is central to apoptosis, but the events leading up to it are disputed. The mitochondrial membrane potential has been reported to decrease, increase or remain unc...

BCL-2 family members and the mitochondria in apoptosis.

Genes Dev. 13 , 1899, (1999)

Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-kappaB.

Oncogene 18 , 747, (1999)

Reactive oxygen species (ROS) play an important role in cell death induced by many different stimuli. This study shows that hydrogen peroxide-induced apoptosis in T-cells did not require tyrosine kina...


More Articles


Related Compounds

  • Bongkrekic acid
  • Octanethioic acid S-propyl ester
  • Hexanethioic acid S-decyl ester
  • Thiopropionic acid S-undecyl ester
  • trisporic acid
  • Benzenesulfonic acid, 3,3-methylenebis2,4(or 4,6)-dihydroxyphenyleneazobis-, potassium sodium salt
  • benzyl N-(4-bromo-5,6,7,8-tetrahydronaphthalen-1-yl)carbamate
  • Benzyl 4-(2-hydroxypropyl)-2-methylpiperazine-1-carboxylate
  • tert-butyl N-(4,5-dibromopyrimidin-2-yl)carbamate
  • 2-Bromo-1-fluoro-4-(4-fluorophenoxy)benzene
  • (4R)-4-[(methylamino)methyl]-1,3-oxazolidin-2-one
  • 2-(N-ethylacetamido)-1,3-thiazole-4-carboxylic acid
  • Ethyl 3-amino-4-cyclopentyl-2-hydroxybutanoate hydrochloride
  • Tert-butyl 2-amino-2-(1,3-thiazol-4-yl)acetate
  • benzyl N-(8-hydroxyquinolin-3-yl)carbamate
  • 3-Chloro-4-acetamidopyridine-2-carboxylic acid
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