Ethylene glycol monoethyl ether acetate

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Names

[ CAS No. ]:
111-15-9

[ Name ]:
Ethylene glycol monoethyl ether acetate

[Synonym ]:
EEA
egeea
EE ACETATE
2-Ethoxyethanol Acetate
ethylene glycol ethyl ether acetate
MFCD00009251
1-Acetoxy-2-ethoxyethane
Cellosolve Acetate
Acetic Acid 2-Ethoxyethyl Ester
CSAC
ethoxyacetate
2-eea
Ethyl Glycol Acetate
oxytolacetate
2-ethoxyethyl
EINECS 203-839-2
Sensolve EEA
2-Ethoxyethyl Acetate
acetoxy-2-ethoxyethane
2-Ethoxyethylacetate
Ethylene Glycol Monoethyl Ether Acetate

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
156.1±0.0 °C at 760 mmHg

[ Melting Point ]:
-61 °C

[ Molecular Formula ]:
C₆H₁₂O₃

[ Molecular Weight ]:
132.158

[ Flash Point ]:
50.6±11.4 °C

[ Exact Mass ]:
132.078644

[ PSA ]:
35.53000

[ LogP ]:
0.45

[ Vapour density ]:
4.6 (vs air)

[ Vapour Pressure ]:
2.9±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.401

[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents, strong acids, strong bases, nitrates.

[ Water Solubility ]:
230 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KK8225000

CHEMICAL NAME :: Ethanol, 2-ethoxy-, acetate

CAS REGISTRY NUMBER :: 111-15-9

BEILSTEIN REFERENCE NO. :: 1748677

LAST UPDATED :: 199712

DATA ITEMS CITED :: 59

MOLECULAR FORMULA :: C6-H12-O3

MOLECULAR WEIGHT :: 132.18

WISWESSER LINE NOTATION :: 2O2OV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/13/1967

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/13/1967 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 53(10),78,1988

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 12100 mg/m3/8H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 20,364,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1420 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SCCUR* Shell Chemical Company. Unpublished Report. (2401 Crow Canyon Rd., San Romon, CA 94583) Volume(issue)/page/year: -,2,1961

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 42,355,1931

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1950 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0682-0450

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2000 ppm/4H

TOXIC EFFECTS :: Kidney, Ureter, Bladder - hematuria

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 51,117,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 10500 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/13/1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1910 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Gastrointestinal - other changes Kidney, Ureter, Bladder - other changes

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 23,259,1941

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: >19460 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0682-0450 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 600 ppm/7H

SEX/DURATION :: female 7-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetal death

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0682-0450

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 200 ppm/6H

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - respiratory system

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 10,20,1988

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 300 ppm/6H

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system Reproductive - Specific Developmental Abnormalities - urogenital system

REFERENCE :: UCRR** Union Carbide Research Report. (Union Carbide Corp., Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 09OCT1984

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 50 mg/kg/4H

SEX/DURATION :: female 1-19 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :: FAVUAI Fiziologicheski Aktivnye Veshchestva. Physiologically Active Substances. (Izdatel'stvo Naukova Dumka, Kiev, USSR) No.1- 1966- Volume(issue)/page/year: 21,30,1989

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 50 ppm/6H

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: UCRR** Union Carbide Research Report. (Union Carbide Corp., Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 09OCT1984

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

DOSE :: 70 gm/kg

SEX/DURATION :: female 7-16 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)

REFERENCE :: EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 57,69,1984

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

DOSE :: 70 gm/kg

SEX/DURATION :: female 7-16 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system

REFERENCE :: EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 57,69,1984

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 25 gm/kg

SEX/DURATION :: male 25 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct

REFERENCE :: SAIGBL Sangyo Igaku. Japanese Journal of Industrial Health. (Nippon Sangyo Eisei Igakkai, Kosu Eisei Bldg., 1-29-8, Shinjuku, Shinjuku-ku, Tokyo 160, Japan) V.1- 1959- Volume(issue)/page/year: 21,29,1979

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 100 gm/kg

SEX/DURATION :: male 25 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands

REFERENCE :: SAIGBL Sangyo Igaku. Japanese Journal of Industrial Health. (Nippon Sangyo Eisei Igakkai, Kosu Eisei Bldg., 1-29-8, Shinjuku, Shinjuku-ku, Tokyo 160, Japan) V.1- 1959- Volume(issue)/page/year: 21,29,1979

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 200 ppm/6H

SEX/DURATION :: female 6-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system Reproductive - Specific Developmental Abnormalities - respiratory system Reproductive - Specific Developmental Abnormalities - urogenital system

REFERENCE :: UCRR** Union Carbide Research Report. (Union Carbide Corp., Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 09OCT1984

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 200 ppm/6H

SEX/DURATION :: female 6-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)

REFERENCE :: UCRR** Union Carbide Research Report. (Union Carbide Corp., Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 09OCT1984

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 100 ppm/6H

SEX/DURATION :: female 6-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: UCRR** Union Carbide Research Report. (Union Carbide Corp., Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 09OCT1984

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 100 ppm/6H

SEX/DURATION :: female 6-18 day(s) after conception

REFERENCE :: EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 57,33,1984 *** REVIEWS *** ACGIH TLV-TWA 27 mg/m3 (5 ppm) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 TOXICOLOGY REVIEW FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 13,747,1989 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 100 ppm (540 mg/m3) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,101,1971 OSHA PEL (Gen Indu):8H TWA 100 ppm (540 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 100 ppm (540 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 100 ppm (540 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 100 ppm (540 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 5 ppm (27 mg/m3);Skin JAN 1993 OEL-BELGIUM:TWA 5 ppm (27 mg/m3);Skin JAN 1993 OEL-DENMARK:TWA 5 ppm (27 mg/m3);Skin JAN 1993 OEL-FINLAND:TWA 50 ppm (270 mg/m3);STEL 100 ppm (540 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 5 ppm (27 mg/m3);Skin JAN 1993 OEL-GERMANY:TWA 20 ppm (110 mg/m3);Skin JAN 1993 OEL-HUNGARY:TWA 25 mg/m3;STEL 50 mg/m3;Skin JAN 1993 OEL-JAPAN:TWA 5 ppm (27 mg/m3);Skin JAN 1993 OEL-THE NETHERLANDS:TWA 5 ppm (27 mg/m3);Skin JAN 1993 OEL-THE PHILIPPINES:TWA 100 ppm (540 mg/m3);Skin JAN 1993 OEL-POLAND:TWA 100 mg/m3 JAN 1993 OEL-RUSSIA:TWA 5 ppm JAN 1993 OEL-SWEDEN:TWA 5 ppm (30 mg/m3);STEL 10 ppm (50 mg/m3);Skin JAN 1993 OEL-SWITZERLAND:TWA 5 ppm (27 mg/m3);STEL 10 ppm (54 mg/m3);Skin JAN 1993 OEL-TURKEY:TWA 100 ppm (540 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 10 ppm (54 mg/m3);Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO EGEEA-air:10H TWA 0.5 ppm (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4063 No. of Facilities: 38895 (estimated) No. of Industries: 228 No. of Occupations: 127 No. of Employees: 321063 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4063 No. of Facilities: 16901 (estimated) No. of Industries: 149 No. of Occupations: 103 No. of Employees: 265104 (estimated) No. of Female Employees: 51020 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H302 + H312 + H332-H360FD

[ Precautionary Statements ]:
P201-P280-P308 + P313

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T:Toxic

[ Risk Phrases ]:
R10;R20/21/22;R60;R61

[ Safety Phrases ]:
S53-S45

[ RIDADR ]:
UN 1172 3/PG 3

[ WGK Germany ]:
1

[ RTECS ]:
KK8225000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2915390090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

1,2-diacetoxy-1-ethoxy-ethane
acetic acid,2-ethoxyethenol
(E)-2-Ethoxyvinylacetate
2-Ethoxyethanol
ethyl acetate
1-ethoxy-2-methoxymethoxy-ethane
lead tetraacetate
ketene
Ethanoic anhydride
Acetyl chloride

DownStream

1,2-Ethanediyl 1-acetate 2-formate
glycol diacetate
Ethyl formate
2-Ethoxyethanol
acetic acid
3,3'-(Ethane-1,1-diyl)bis(1H-indole)
Acetic acid 2,2-bis(1H-indole-3-yl)ethyl ester

Customs

[ HS Code ]: 2915390090

[ Summary ]:
2915390090. esters of acetic acid. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:5.5%. General tariff:30.0%

Articles

Histologic investigation of gingival epithelium implantation and the nonincision placement of miniscrews.

Int. J. Oral Maxillofac. Implants 29(5) , 1137-42, (2014)

This study investigated whether the nonincision placement of miniscrews could lead to ectopic implantation of epithelium at the bone-implant interface and, if so, whether the epithelial cells could su...

Impact of chronic hypoxemia on blood flow to the brain, heart, and adrenal gland in the late-gestation IUGR sheep fetus.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 308(3) , R151-62, (2015)

In the fetus, there is a redistribution of cardiac output in response to acute hypoxemia, to maintain perfusion of key organs, including the brain, heart, and adrenal glands. There may be a similar re...

Placental perfusion in uterine ischemia model as evaluated by dynamic contrast enhanced MRI.

J. Magn. Reson. Imaging 42 , 666-72, (2015)

To validate DCE MRI method of placental perfusion estimation and to demonstrate application of the method in a rabbit model of fetal antenatal hypoxia-ischemia.Placental perfusion was estimated by dyn...

diethylene glycol monoethyl ether acetate
2-ethoxyethanol,propanoic acid
Hexanoic acid,2-ethoxyethyl ester
2-Ethoxyethyl acrylate
2-ETHOXYETHYL P-TOLUENESULFONATE
TRICHLOROACETIC ACID 2-ETHOXYETHYL ESTER
trans-2-[(4-Ethylphenyl)amino]cyclobutan-1-ol
trans-2-({Octahydrocyclopenta[c]pyrrol-2-yl}amino)cyclobutan-1-ol
trans-2-[(2-Ethylphenyl)amino]cyclobutan-1-ol
1-[trans-2-Hydroxycyclobutyl]piperazin-2-one
4-{[trans-2-Hydroxycyclobutyl](methyl)amino}phenol
trans-2-[(3-Methoxypropyl)amino]cyclobutan-1-ol
trans-2-(4-Ethylpiperazin-1-yl)cyclobutan-1-ol
trans-2-{[(3-Methoxyphenyl)methyl]amino}cyclobutan-1-ol
trans-2-(1,4-Diazepan-1-yl)cyclobutan-1-ol
trans-2-[4-(Dimethylamino)piperidin-1-yl]cyclobutan-1-ol

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