N,N,N',N`-Tetramethylhexanediamine

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Names

[ CAS No. ]:
111-18-2

[ Name ]:
N,N,N',N`-Tetramethylhexanediamine

[Synonym ]:
N,N,N',N'-Tetramethylhexane-1,6-diamine
N,N,N',N'-TetraMethyl-1,6-diaMinohexane
EINECS 203-842-9
1,6-Hexanediamine, N,N,N,N-tetramethyl-
N,N,N‘,N‘-Tetramethyl-1,6-hexanediamine
1,6-Bis(dimethylamino)hexane
N1,N1,N6,N6-Tetramethylhexane-1,6-diamine
MFCD00008339
N,N,N',N`-Tetramethylhexanediamine
N,N,N',N'-Tetramethylhexamethyl-enediamine
N,N,N',N'-Tetramethyl-1,6-hexanediamine

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
209.5±8.0 °C at 760 mmHg

[ Melting Point ]:
-46ºC

[ Molecular Formula ]:
C10H24N2

[ Molecular Weight ]:
172.311

[ Flash Point ]:
73.9±0.0 °C

[ Exact Mass ]:
172.193954

[ PSA ]:
6.48000

[ LogP ]:
1.50

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.449

[ Water Solubility ]:
miscible | miscible

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MO1370000
CHEMICAL NAME :
1,6-Hexanediamine, N,N,N',N'-tetramethyl-
CAS REGISTRY NUMBER :
111-18-2
BEILSTEIN REFERENCE NO. :
1738567
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C10-H24-N2
MOLECULAR WEIGHT :
172.36
WISWESSER LINE NOTATION :
1N1&6N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536039
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536039 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
297 uL/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Gastrointestinal - ulceration or bleeding from stomach Musculoskeletal - other changes
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536039
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
141 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJNEAQ International Journal of Neuropharmacology. (New York, NY) V.1-8, 1962-69. For publisher information, see NEPHBW. Volume(issue)/page/year: 8,131,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
492 uL/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Gastrointestinal - other changes Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536039

Safety Information

[ Symbol ]:

GHS05, GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301 + H311-H314-H330-H411

[ Precautionary Statements ]:
P260-P273-P280-P284-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
R22;R24;R34

[ Safety Phrases ]:
26-36/37/39-45

[ RIDADR ]:
UN 3390

[ WGK Germany ]:
1

[ RTECS ]:
MO1370000

[ Packaging Group ]:
III

[ HS Code ]:
2921290000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1,6-Dibromohexane
  • Dimethylamine
  • tetra-N-methyl-hex-3-ynediyldiamine
  • tetra-N-methyl-hex-2-ynediyldiamine
  • 1-dimethylamino-2-propyne
  • 3-Chloro-N,N-dimethylpropan-1-amine
  • 1,6-Hexanediamine
  • Formaldehyde
  • N1,N1,N6,N6-Tetramethyladipamide
  • 1,6-diiodohexane

DownStream

  • N,N'-bis(decyldimethyl)-1,6-hexanediammonium
  • benzhydryl-[6-[benzhydryl(dimethyl)azaniumyl]hexyl]-dimethylazanium,dibromide
  • N-Nitrosodimethylamine
  • Hexafluronium Bromide
  • ethyl-[6-[ethyl(dimethyl)azaniumyl]hexyl]-dimethylazanium,dibromide
  • dodecyl-[6-(dodecyl-dimethyl-ammonio)hexyl]-dimethyl-azanium
  • (2-heptoxy-2-oxoethyl)-[6-[(2-heptoxy-2-oxoethyl)-dimethylazaniumyl]hexyl]-dimethylazanium,dichloride
  • 4-(4-tert-butylphenoxy)butyl-[6-[4-(4-tert-butylphenoxy)butyl-dimethylazaniumyl]hexyl]-dimethylazanium,dibromide
  • hexamethonium iodide

Customs

[ HS Code ]: 2921290000

[ Summary ]:
2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Related Compounds

  • n,n,n',n'-tetramethyl-l-cystine
  • N1,N1,N6,N6-Tetramethyladipamide
  • N,N,N',N'-tetrakis(2-ethylhexyl)methanediamine
  • N,N,N',N'-Tetramethyl-N''-(4-nitrophenyl)phosphoric triamide
  • N,N,N',N'-Tetraisopropylthioharnstoff
  • (N,N,N',N'-tetramethylethylenediamine)nickel(CO3)
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 1-(5-Amino-4-ethyl-1,3-thiazol-2-yl)-2,2-difluoroethan-1-one
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide