2-(Allyloxy)ethanol

Suppliers

Names

[ CAS No. ]:
111-45-5

[ Name ]:
2-(Allyloxy)ethanol

[Synonym ]:
allylcellosolve
ALLYL GLYCOL
Ethanol,2-(allyloxy)
MFCD00020607
Ethylene glycol monoallyl ether
2-Prop-2-enoxyethanol
EINECS 203-871-7
Ethylene glycol allyl ether
2-Alloxyethanol
2-(Allyloxy)ethanol
usafdo-47
allyloxyethanol
2-(allyloxy)ethan-1-ol
2-(allyloxy)-ethano
Ethanol, 2-(2-propen-1-yloxy)-
O-allyl-ethylene glycol

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
158.5±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₅H₁₀O₂

[ Molecular Weight ]:
102.132

[ Flash Point ]:
55.0±14.6 °C

[ Exact Mass ]:
102.068077

[ PSA ]:
29.46000

[ LogP ]:
0.10

[ Vapour Pressure ]:
0.9±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.426

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KJ5425000

CHEMICAL NAME :: Ethanol, 2-(allyloxy)-

CAS REGISTRY NUMBER :: 111-45-5

BEILSTEIN REFERENCE NO. :: 1742145

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C5-H10-O2

MOLECULAR WEIGHT :: 102.15

WISWESSER LINE NOTATION :: Q2O2U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,629,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,629,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3050 mg/kg

TOXIC EFFECTS :: Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (2),41,1993

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 7,687,1955

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S39-S45-S36/37/39

[ RIDADR ]:
NA 1993 / PGIII

[ WGK Germany ]:
2

[ RTECS ]:
KJ5425000

[ HS Code ]:
2909499000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Ethylene glycol
allyl bromide
Propynol Ethoxylate
ALLYL CHLORIDE
DIALLYL CARBONATE
4-Penten-1-ol
ETHYLENE OXIDE
Allyl alcohol
2-Vinyl-1,3-dioxolane
2-Chloroethanol

DownStream

2,2'-(((1,1,3,3-tetramethyldisiloxane-1,3-diyl)bis(propane-3,1-diyl))bis(oxy))diethanol
2-aminobenzoic acid,2-prop-2-enoxyethanol
Ethylene glycol
2-[2-(2-prop-2-enoxyethoxy)ethoxy]ethanol
2-(Allyloxy)EthoxyTrimethylsilane
3-(2-BROMO-ETHOXY)-PROPENE
allyl vinyl ether
Allyldiglycol
2-Ethyl-1,3-dioxolane
hex-5-en-1-ol,methanesulfonic acid

Customs

[ HS Code ]: 2909499000

[ Summary ]:
2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

[Evaluation of maximal permissible concentration of 2-allyl oxyethanol in the atmospheric air].

Gig. Sanit. (2) , 4-6, (1995)

The threshold irritable concentration of 2-allyl oxyethanol (2-AOE) in ambient air was determined at the level of 0.68 mg/m3. The threshold of chronic effect of 2-AOE is 0.075 mg/m3. The mean daily pe...

Modulation of the cell kinetics of pig skin by the topical application of evening primrose oil or Lioxasol.

Cell Prolif. 30(8-9) , 311-23, (1997)

The daily topical application of two compounds, a cream containing 10% evening primrose oil (EPO) and Lioxasol (a compound used clinically to treat radiation burns), resulted in increased cell prolife...