Efonidipine

Suppliers

Names

[ CAS No. ]:
111011-63-3

[ Name ]:
Efonidipine

[Synonym ]:
3-Pyridinecarboxylic acid, 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[phenyl(phenylmethyl)amino]ethyl ester, (4S)-
2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylate
Efonidipine HCl
3-(benzyl-(phenyl)amino)ethyl-5-(5,5-dimethyl-2-oxo-1,3-dioxaphosphorinane-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine
2-[Benzyl(phenyl)amino]ethyl (4S)-5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3-pyridinecarboxylate
Efonidipine [INN]
Efonidipine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
746.9±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C34H38N3O7P

[ Molecular Weight ]:
631.655

[ Flash Point ]:
405.5±32.9 °C

[ Exact Mass ]:
631.244751

[ PSA ]:
132.73000

[ LogP ]:
6.99

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.625

[ Storage condition ]:
-20℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-methoxy-5,5-dimethyl-1,3,2-dioxaphosphorinane
  • 2-acetonyl-5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinane
  • Neopentyl glycol

DownStream

Related Compounds

  • Efonidipine
  • Efonidipine HCl
  • Efonidipine Hydrochloride
  • Efonidipine hydrochloride monoethanolate
  • 1-((1R,5S)-8-azabicyclo[3.2.1]oct-2-en-8-yl)-2-(2,4-dichlorophenoxy)ethanone
  • N-(3,4-Dimethylphenyl)-8-azabicyclo[3.2.1]oct-2-ene-8-carboxamide
  • N-(2H-1,3-benzodioxol-5-yl)-8-azabicyclo[3.2.1]oct-2-ene-8-carboxamide
  • N-(2,3-Dimethoxyphenyl)-8-azabicyclo[3.2.1]oct-2-ene-8-carboxamide
  • (1R,5S)-8-((3-fluorobenzyl)sulfonyl)-8-azabicyclo[3.2.1]oct-2-ene
  • (1R,5S)-8-((4-fluoro-3-methylphenyl)sulfonyl)-8-azabicyclo[3.2.1]oct-2-ene
  • (1R,5S)-8-((3-chloro-4-fluorophenyl)sulfonyl)-8-azabicyclo[3.2.1]oct-2-ene
  • (1R,5S)-8-((5,6,7,8-tetrahydronaphthalen-2-yl)sulfonyl)-8-azabicyclo[3.2.1]oct-2-ene
  • (4-Methylthiophen-2-yl)(3-(thiazol-2-yloxy)azetidin-1-yl)methanone
  • N-phenyl-4-(thiophen-3-yl)piperidine-1-carboxamide
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