Efonidipine

Suppliers

Names

[ CAS No. ]:
111011-63-3

[ Name ]:
Efonidipine

[Synonym ]:
3-Pyridinecarboxylic acid, 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[phenyl(phenylmethyl)amino]ethyl ester, (4S)-
2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylate
Efonidipine HCl
3-(benzyl-(phenyl)amino)ethyl-5-(5,5-dimethyl-2-oxo-1,3-dioxaphosphorinane-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine
2-[Benzyl(phenyl)amino]ethyl (4S)-5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3-pyridinecarboxylate
Efonidipine [INN]
Efonidipine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
746.9±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C34H38N3O7P

[ Molecular Weight ]:
631.655

[ Flash Point ]:
405.5±32.9 °C

[ Exact Mass ]:
631.244751

[ PSA ]:
132.73000

[ LogP ]:
6.99

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.625

[ Storage condition ]:
-20℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-methoxy-5,5-dimethyl-1,3,2-dioxaphosphorinane
  • 2-acetonyl-5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinane
  • Neopentyl glycol

DownStream

Related Compounds

  • Efonidipine
  • Efonidipine HCl
  • Efonidipine Hydrochloride
  • Efonidipine hydrochloride monoethanolate
  • (1R)-1-[2-chloro-5-(trifluoromethyl)phenyl]-2,2,2-trifluoroethan-1-ol
  • 3-[1-(4-Bromophenyl)cyclopropyl]-2,2-dimethylcyclopropan-1-amine
  • 2-Chloro-1-(2-methoxy-4-nitrophenyl)ethan-1-ol
  • [1-(4-chloro-1-methyl-1H-imidazol-5-yl)-2,2-dimethylcyclopropyl]methanol
  • rac-[(1R,3R)-2,2-dimethyl-3-(5-phenylthiophen-2-yl)cyclopropyl]methanamine
  • 4-(1,3-Benzothiazol-2-yl)-1,1-difluorobutan-2-ol
  • 3-(4-Bromo-2-methoxyphenyl)-2,2-dimethylpropan-1-amine
  • tert-butyl N-(but-3-yn-2-yl)-N-ethylcarbamate
  • 3-[(3,3-Difluorocyclobutyl)methyl]morpholine
  • 1-[1-(4-Ethoxyphenyl)cyclopropyl]cyclopropan-1-amine
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