Efonidipine

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Names

[ CAS No. ]:
111011-63-3

[ Name ]:
Efonidipine

[Synonym ]:
3-Pyridinecarboxylic acid, 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[phenyl(phenylmethyl)amino]ethyl ester, (4S)-
2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylate
Efonidipine HCl
3-(benzyl-(phenyl)amino)ethyl-5-(5,5-dimethyl-2-oxo-1,3-dioxaphosphorinane-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine
2-[Benzyl(phenyl)amino]ethyl (4S)-5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3-pyridinecarboxylate
Efonidipine [INN]
Efonidipine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
746.9±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C34H38N3O7P

[ Molecular Weight ]:
631.655

[ Flash Point ]:
405.5±32.9 °C

[ Exact Mass ]:
631.244751

[ PSA ]:
132.73000

[ LogP ]:
6.99

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.625

[ Storage condition ]:
-20℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-methoxy-5,5-dimethyl-1,3,2-dioxaphosphorinane
  • 2-acetonyl-5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinane
  • Neopentyl glycol

DownStream

Related Compounds

  • Efonidipine
  • Efonidipine HCl
  • Efonidipine Hydrochloride
  • Efonidipine hydrochloride monoethanolate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • Tert-butyl 3-(1H-imidazol-4-YL)piperidine-1-carboxylate
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide