[chloro(methyl)phosphoryl]methane

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Names

[ CAS No. ]:
1111-92-8

[ Name ]:
[chloro(methyl)phosphoryl]methane

[Synonym ]:
[chloro(methyl)phosphoryl]methane
EINECS 214-187-3
MFCD00002078

Chemical & Physical Properties

[ Density]:
1.158 g/cm3

[ Boiling Point ]:
204ºC at 760 mmHg

[ Melting Point ]:
65-71ºC(lit.)

[ Molecular Formula ]:
C2H6ClOP

[ Molecular Weight ]:
112.49500

[ Flash Point ]:
77.2ºC

[ Exact Mass ]:
111.98400

[ PSA ]:
26.88000

[ LogP ]:
1.76290

[ Vapour Pressure ]:
0.385mmHg at 25°C

[ Index of Refraction ]:
1.39

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C: Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
26-27-28-36/37/39-45

[ RIDADR ]:
UN 3261 8

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ HS Code ]:
2903199000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Dimethylphosphinic acid
  • tetramethylbiphosphine disulfide
  • tetramethyldiphosphine dioxide
  • N-dimethylphosphoryl-N-methylmethanamine

DownStream

  • Ridaforolimus (Deforolimus, MK-8669)
  • Rapamycin (Sirolimus)
  • 4-Methylaniline hydrochloride
  • P,P-dimethyl-N-phenylphosphinic amide
  • Anilinium chloride
  • Dimethylphosphinic acid
  • [dimethylphosphoryloxy(methyl)phosphoryl]methane
  • 1-dimethylphosphoryloxy-4-nitrobenzene
  • dimethyl ethylphosphonite

Customs

[ HS Code ]: 2903199000

[ Summary ]:
2903199000 other saturated chlorinated derivatives of acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Pyridinolysis of Diethyl Phosphinic Chloride in Acetonitrile. Dey NK, et al.

Bull. Korean Chem. Soc. 32(2) , 709-12, (2011)

Kinetics and mechanism of the aminolysis of dimethyl and methyl phenyl phosphinic chlorides with anilines. Dey NK, et al.

J. Phys. Org. Chem. 22(5) , 425-30, (2009)

Dialkylethynylphosphine oxides; synthesis and reactions. Hagens W, et al.

Rec. Trav. Chim. 88(1) , 71-85, (1969)


More Articles

Related Compounds

  • chloro-[chloro(methyl)phosphoryl]methane
  • [chloro(methyl)phosphoryl]oxymethane
  • [chloro(methyl)phosphoryl]oxybenzene
  • [dimethylphosphoryloxy(methyl)phosphoryl]methane
  • [fluoro(methyl)phosphoryl]methane
  • 1-[chloro(methyl)phosphoryl]oxypentane
  • 2-Amino-1-(4-bromofuran-2-yl)ethan-1-one
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 5,5,5-Trifluoropent-2-enal
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine