bleomycin A5
Suppliers
Names
[ CAS No. ]:
11116-32-8
[ Name ]:
bleomycin A5
[Synonym ]:
N1-(3-((4-Aminobutyl)amino)propyl)bleomycinamide
Pingyangmycin A5
(2R,3S,4S,5R,6R)-2-{[(2R,3S,4S,5S,6S)-2-[(1R,2S)-2-[({6-Amino-2-[(1S)-3-amino-1-{[(2S)-2,3-diamino-3-oxopropyl]amino}-3-oxopropyl]-5-methyl-4-pyrimidinyl}carbonyl)amino]-3-{[(2R,3S,4R)-5-{[(2S,3R)-1-({2-[4-({3-[(4-aminobutyl)amino]propyl}carbamoyl)-2,4'-bi-1,3-thiazol-2'-yl]ethyl}amino)-3-hydroxy-1-oxo-2-butanyl]amino}-3-hydroxy-4-methyl-5-oxo-2-pentanyl]amino}-1-(1H-imidazol-4-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-
Zhengguanmycin A5
Bleomycin A5
bleomycetin
2-({2-[2-{[(6-Amino-2-{3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl}-5-methyl-4-pyrimidinyl)carbonyl]amino}-3-[(5-{[1-({2-[4-({3-[(4-aminobutyl)amino]propyl}carbamoyl)-2,4'-bi-1,3-thiazol-2'-yl]ethyl}amino)-3-hydroxy-1-oxo-2-butanyl]amino}-3-hydroxy-4-methyl-5-oxo-2-pentanyl)amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl}oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl
Bleomycinamide,N1-[3-[(4-aminobutyl)amino]propyl]
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Molecular Formula ]:
C57H89N19O21S2
[ Molecular Weight ]:
1440.561
[ Exact Mass ]:
1439.592163
[ PSA ]:
721.60000
[ LogP ]:
-2.35
[ Index of Refraction ]:
1.681
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EC5990500
- CHEMICAL NAME :
- Bleomycinamide, N'-(3-((4-aminobutyl)amino)propyl)-
- CAS REGISTRY NUMBER :
- 11116-32-8
- LAST UPDATED :
- 199506
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C57-H89-N19-O21-S2
- MOLECULAR WEIGHT :
- 1440.77
- WISWESSER LINE NOTATION :
- T6OTJ BQ CQ DOVZ EQ FO- CT6OTJ DQ EQ FQ BOY- DT5M CNJ&YVMY1&YQY1&VNYYQ1&VM2- BT5N CSJ E-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 192 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature increase
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 400 ug/L
- REFERENCE :
- HKXUDL Huanjing Kexue Xuebao. Environmental Sciences Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1981- Volume(issue)/page/year: 3,78,1983