2-Chloro-5-ethylpyrimidine

Suppliers

Names

[ CAS No. ]:
111196-81-7

[ Name ]:
2-Chloro-5-ethylpyrimidine

[Synonym ]:
MFCD00799503
2-Chloro-5-Ethyl Pyrimidine
2-Chloro-5-ethylpyrimidine
Pyrimidine, 2-chloro-5-ethyl-

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
249.4±9.0 °C at 760 mmHg

[ Melting Point ]:
18°C

[ Molecular Formula ]:
C6H7ClN2

[ Molecular Weight ]:
142.586

[ Flash Point ]:
128.7±4.3 °C

[ Exact Mass ]:
142.029770

[ PSA ]:
25.78000

[ LogP ]:
1.35

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.523

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2,4-Dichloro-5-ethylpyrimidine
  • Triethylaluminum
  • 5-Bromo-2-chloropyrimidine
  • 5-Ethyluracil

DownStream

  • 1-(5-Ethyl-2-pyrimidinyl)-4-piperidinol

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Effects of various bases on acid-catalyzed amination of 2-chloro-5-ethylpyrimidine: synthesis of PPARpan agonist GW693085.

J. Org. Chem. 75(11) , 3904-7, (2010)

A unique buffering effect of various bases, i-Pr(2)NEt and CaCO(3) in particular, was observed for the acid-catalyzed chloro displacement of 2-chloro-5-ethylpyrimidine with a 2-methyl-2-phenylpropanam...

239. The Dimroth rearrangement. Part I. Some alkylated 2-iminopyrimidines. Brown DJ and Harper JS.

J. Chem. Soc. , 1276-84, (1963)


More Articles

Related Compounds

  • 2-chloro-5-phenylaniline
  • 2-chloro-5-(2-methyl-1,3-thiazol-4-yl)benzoic acid
  • (2-chloro-5-nitrophenyl)-(3-nitrophenyl)methanone
  • 2-chloro-5-(2-ethoxyethenyl)pyrimidin-4-amine
  • 2-chloro-5-hydroxybenzenesulfonic acid
  • 2-Chloro-5-fluorobenzonitrile
  • 1-(4-chlorophenyl)-3-(4-((4-(3-(m-tolyl)-1,2,4-oxadiazol-5-yl)-1H-imidazol-1-yl)methyl)phenyl)urea
  • 1-(3-methoxyphenyl)-3-(4-((4-(3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl)-1H-imidazol-1-yl)methyl)phenyl)urea
  • 1-(3-methoxyphenyl)-3-(4-((4-(3-(m-tolyl)-1,2,4-oxadiazol-5-yl)-1H-imidazol-1-yl)methyl)phenyl)urea
  • 1-(4-((4-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)-1H-imidazol-1-yl)methyl)phenyl)-3-(3-methoxyphenyl)urea
  • 1-(4-ethoxyphenyl)-3-(4-((4-(3-(m-tolyl)-1,2,4-oxadiazol-5-yl)-1H-imidazol-1-yl)methyl)phenyl)urea
  • 1-(3,4-dimethylphenyl)-3-(4-((4-(3-(p-tolyl)-1,2,4-oxadiazol-5-yl)-1H-imidazol-1-yl)methyl)phenyl)urea
  • 1-(4-((4-(3-(p-tolyl)-1,2,4-oxadiazol-5-yl)-1H-imidazol-1-yl)methyl)phenyl)-3-(2-(trifluoromethyl)phenyl)urea
  • 1-(4-((4-(3-(m-tolyl)-1,2,4-oxadiazol-5-yl)-1H-imidazol-1-yl)methyl)phenyl)-3-(2-(trifluoromethyl)phenyl)urea
  • 1-(2-ethoxyphenyl)-3-(4-((4-(3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-1H-imidazol-1-yl)methyl)phenyl)urea
  • 1-(2-ethoxyphenyl)-3-(4-((4-(3-(m-tolyl)-1,2,4-oxadiazol-5-yl)-1H-imidazol-1-yl)methyl)phenyl)urea
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.