Naltrindole hydrochloride

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Names

[ CAS No. ]:
111469-81-9

[ Name ]:
Naltrindole hydrochloride

[Synonym ]:
MFCD00069313
NTI
NTI hydrochloride
Naltrindole (hydrochloride)

Chemical & Physical Properties

[ Boiling Point ]:
664.2ºC at 760mmHg

[ Molecular Formula ]:
C26H27ClN2O3

[ Molecular Weight ]:
450.95700

[ Flash Point ]:
355.5ºC

[ Exact Mass ]:
450.17100

[ PSA ]:
68.72000

[ LogP ]:
4.31250

[ Vapour Pressure ]:
1.51E-18mmHg at 25°C

[ Storage condition ]:
2-8℃

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Naltrexone Hydrochloride
  • Phenylhydrazine hydrochloride

DownStream

Articles

Naltrindole, a highly selective and potent non-peptide delta opioid receptor antagonist.

Eur. J. Pharmacol. 146 , 185, (1988)

Acute delta-opioid receptor activation induces CREB phosphorylation in NG108-15 cells.

Eur. J. Pharmacol. 390 , 1-6, (2000)

A growing body of evidence supports an important role of the transcription factor cAMP responsive element binding protein (CREB) in mediating opioid-induced changes in the cAMP pathway. Regulation of ...

Characterization of delta-opioid receptors and effect of enkephalins on IRD 98 rat epithelial intestinal cell line.

Pflugers Arch. 439 , 547-554, (2000)

Using 3H-Tyr-D-Ala-Gly-Phe-D-Leu-OH (3H-DADLE) as a radioligand, delta-opioid binding sites on the IRD 98 rat epithelial cell line were identified. These sites were found to be reversible, saturable, ...


More Articles

Related Compounds

  • NALTRINDOLE ISOTHIOCYANATE
  • Tyrocidine, hydrochloride
  • Triprolidine hydrochloride
  • Minoxidil hydrochloride
  • neomycin hydrochloride
  • dodecylamine hydrochloride
  • 5-[(2R)-piperidin-2-yl]-1,3-oxazole-4-carboxylic acid
  • (7-Fluoro-4-methylisoquinolin-1-yl)methanol
  • 1-Cyclopropyl-4-(prop-2-en-1-yl)piperidine-4-carboxylic acid
  • rac-(3R,5R)-5-({[(benzyloxy)carbonyl]amino}methyl)oxolane-3-carboxylic acid
  • 1-(Bromomethyl)-1-ethyl-3,3-difluorocyclobutane
  • 3-(Chloromethyl)-3-(2,2-difluoroethyl)-2-methyloxolane
  • 1-(Bromomethyl)-1-(4,4-difluorobutyl)cyclopropane
  • 1-(Bromomethyl)-1-(4-methylpent-3-en-1-yl)cyclobutane
  • 2-(3-Bromopropyl)-5-chloropyridine
  • 3-{[1-(Chloromethyl)-2-methylcyclopropyl]methyl}thiophene
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