ENLOPLATIN
Suppliers
Names
[ CAS No. ]:
111523-41-2
[ Name ]:
ENLOPLATIN
[Synonym ]:
Enloplatin (USAN/INN)
cis-{Pt(THPDMA)(CBDC)}
{1,1-cyclobutanedicarboxylato(2-)-O,O'}{tetrahydro-4H-pyran-4,4-dimethanamine}platinum(II)
Platinum,[1,1-cyclobutanedi(carboxylato-kO)(2-)](tetrahydro-4H-pyran-4,4-dimethanamine-kN4,kN4')-,(SP-4-2)-(9CI)
Chemical & Physical Properties
[ Boiling Point ]:
241ºC at 760 mmHg
[ Molecular Formula ]:
C13H22N2O5Pt
[ Molecular Weight ]:
481.40200
[ Flash Point ]:
105.5ºC
[ Exact Mass ]:
481.11800
[ PSA ]:
113.87000
[ LogP ]:
1.27040
[ Vapour Pressure ]:
0.0368mmHg at 25°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TP2275818
- CHEMICAL NAME :
- Platinum, (1,1-cyclobutanedicarboxylato(2-))(tetrahydro-4H-pyra n-4,4-dimethanamine-N ,N')-, (SP-4-2)-
- CAS REGISTRY NUMBER :
- 111523-41-2
- LAST UPDATED :
- 199406
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C13-H22-N2-O5-Pt
- MOLECULAR WEIGHT :
- 481.46
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 17,459,1992
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 17,459,1992