ENLOPLATIN

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Names

[ CAS No. ]:
111523-41-2

[ Name ]:
ENLOPLATIN

[Synonym ]:
Enloplatin (USAN/INN)
cis-{Pt(THPDMA)(CBDC)}
{1,1-cyclobutanedicarboxylato(2-)-O,O'}{tetrahydro-4H-pyran-4,4-dimethanamine}platinum(II)
Platinum,[1,1-cyclobutanedi(carboxylato-kO)(2-)](tetrahydro-4H-pyran-4,4-dimethanamine-kN4,kN4')-,(SP-4-2)-(9CI)

Chemical & Physical Properties

[ Boiling Point ]:
241ºC at 760 mmHg

[ Molecular Formula ]:
C13H22N2O5Pt

[ Molecular Weight ]:
481.40200

[ Flash Point ]:
105.5ºC

[ Exact Mass ]:
481.11800

[ PSA ]:
113.87000

[ LogP ]:
1.27040

[ Vapour Pressure ]:
0.0368mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TP2275818
CHEMICAL NAME :
Platinum, (1,1-cyclobutanedicarboxylato(2-))(tetrahydro-4H-pyra n-4,4-dimethanamine-N ,N')-, (SP-4-2)-
CAS REGISTRY NUMBER :
111523-41-2
LAST UPDATED :
199406
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C13-H22-N2-O5-Pt
MOLECULAR WEIGHT :
481.46

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 17,459,1992
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
75 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 17,459,1992

Related Compounds

  • N-((2-(4-(tert-butyl)phenyl)thiazol-5-yl)methyl)cyclopropanamine
  • (2-Cyclobutoxyethyl)(2-methylpropyl)amine
  • Tert-butyl 2-[(2-hydroxy-2-methylpropyl)amino]acetate
  • 1-[2-(Pyrrolidin-3-yl)ethyl]pyrrolidine
  • 4-(2-(Pyrrolidin-3-yl)ethyl)morpholine
  • 1-[(5-Bromo-3-methylpentyl)oxy]heptane
  • 2-Phenyl-2-(pyridin-3-yloxy)-ethylamine
  • 1-{[(Thian-3-yl)amino]methyl}cyclohexan-1-ol
  • (5-Bromo-2-methoxy-3-methylbenzyloxy)(tert-butyl)dimethylsilane
  • (6-Chlorobenzo[1,3]dioxol-5-ylmethyl)cyclopropylamine
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