5-ethoxy-1-(4-nitrophenyl)sulfonyl-pyrrolidin-2-one

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Names

[ CAS No. ]:
111711-48-9

[ Name ]:
5-ethoxy-1-(4-nitrophenyl)sulfonyl-pyrrolidin-2-one

[Synonym ]:
5-Ethoxy-1-((4-nitrophenyl)sulfonyl)-2-pyrrolidinone
2-Pyrrolidinone,5-ethoxy-1-((4-nitrophenyl)sulfonyl)
1-(4-nitro-benzenesulphonyl)-2-oxo-5-ethoxy pyrrolidine

Chemical & Physical Properties

[ Density]:
1.48g/cm3

[ Boiling Point ]:
481ºC at 760mmHg

[ Molecular Formula ]:
C12H14N2O6S

[ Molecular Weight ]:
314.31400

[ Flash Point ]:
244.7ºC

[ Exact Mass ]:
314.05700

[ PSA ]:
117.88000

[ LogP ]:
2.81040

[ Vapour Pressure ]:
2.07E-09mmHg at 25°C

[ Index of Refraction ]:
1.607

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UY5769180
CHEMICAL NAME :
2-Pyrrolidinone, 5-ethoxy-1-((4-nitrophenyl)sulfonyl)-
CAS REGISTRY NUMBER :
111711-48-9
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H14-N2-O6-S
MOLECULAR WEIGHT :
314.34

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 26,403,1991

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-Ethoxy-2-pyrrolidinone
  • nosyl chloride

DownStream

  • 1-(4-aminophenyl)sulfonyl-5-ethoxypyrrolidin-2-one

Related Compounds

  • 5-ethoxy-1-(4-phenylphenyl)sulfonylpyrrolidin-2-one
  • 5-ethoxy-1-(4-phenylmethoxyphenyl)sulfonylpyrrolidin-2-one
  • 5-ethoxy-1-(4-fluorophenyl)sulfonylpyrrolidin-2-one
  • 5-ethoxy-1-(4-hydroxyphenyl)sulfonylpyrrolidin-2-one
  • 5-ethoxy-1-(4-methylphenyl)sulfonylpyrrolidin-2-one
  • 5-ethoxy-1-(4-methoxyphenyl)sulfonylpyrrolidin-2-one
  • 3-(2,5-Dimethylfuran-3-yl)prop-2-enal
  • 4-(2-bromo-4,6-dimethoxyphenyl)-1H-pyrazole
  • 2-Bromo-5-(2-methyl-4-nitrophenoxy)pyridine
  • 3-[4-Methyl-3-(trifluoromethyl)phenyl]oxolane-2,5-dione
  • 2-(2,2,3,3,3-Pentafluoropropyl)morpholine
  • (S)-2-(4-Bromo-2-methylbenzo[d][1,3]dioxol-2-yl)-5-chloropyridine
  • tert-butyl 2-amino-3-(4-chloro-1H-pyrazol-1-yl)butanoate
  • O-[2-(1H-indol-7-yl)propan-2-yl]hydroxylamine
  • 1-{1-[(2-Chloro-6-fluorophenyl)methyl]piperidine-3-carbonyl}-4,4-difluoropiperidine
  • 2-Bromo-3-fluoro-5-hydroxy-4-(methoxymethoxy)benzaldehyde
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