2-Ethoxyethyl ether
Suppliers
Names
[ CAS No. ]:
112-36-7
[ Name ]:
2-Ethoxyethyl ether
[Synonym ]:
EINECS 203-963-7
Diethylene Glycol Diethyl Ether
Diethyldiglycol
Bis(2-ethoxyethyl) Ether
MFCD00009254
Diethyl Carbitol
2-Ethoxyethyl ether
Chemical & Physical Properties
[ Density]:
0.909 g/mL at 25 °C(lit.)
[ Boiling Point ]:
180-190 °C(lit.)
[ Melting Point ]:
-44.3 °C
[ Molecular Formula ]:
C8H18O3
[ Molecular Weight ]:
162.22700
[ Flash Point ]:
160 °F
[ Exact Mass ]:
162.12600
[ PSA ]:
27.69000
[ LogP ]:
1.07600
[ Vapour density ]:
5.6 (vs air)
[ Vapour Pressure ]:
0.758mmHg at 25°C
[ Index of Refraction ]:
n20/D 1.412(lit.)
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents. May form peroxides on exposure to air - test for their presence before heating.
[ Water Solubility ]:
SOLUBLE
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KN3160000
- CHEMICAL NAME :
- Ether, bis(2-ethoxyethyl)
- CAS REGISTRY NUMBER :
- 112-36-7
- BEILSTEIN REFERENCE NO. :
- 1699259
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C8-H18-O3
- MOLECULAR WEIGHT :
- 162.26
- WISWESSER LINE NOTATION :
- 2O2O2O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 4/25/1958 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4970 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 4/25/1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 6700 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 4/25/1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 1850 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic Gastrointestinal - other changes Kidney, Ureter, Bladder - other changes
- REFERENCE :
- JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 23,259,1941 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 24 gm/kg
- SEX/DURATION :
- female 7-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - stillbirth Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
- REFERENCE :
- EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 57,141,1984
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 3 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB88-168257 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84038 No. of Facilities: 1327 (estimated) No. of Industries: 7 No. of Occupations: 8 No. of Employees: 3060 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84038 No. of Facilities: 172 (estimated) No. of Industries: 3 No. of Occupations: 5 No. of Employees: 3489 (estimated) No. of Female Employees: 2128 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H319
[ Precautionary Statements ]:
P305 + P351 + P338
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R19
[ Safety Phrases ]:
S26-S36
[ WGK Germany ]:
2
[ RTECS ]:
KN3160000
[ HS Code ]:
29091900
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2909199090
[ Summary ]:
2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
Articles
Environ. Health Perspect. 57 , 141-6, (1984)
Fifteen glycol ethers were investigated for their potential to cause adverse reproductive toxic effects using an in vivo mouse screening bioassay. Pregnant mice were orally dosed once per day on days ...
Density, viscosity, and surface tension at 293.15 K and liquid-liquid equilibria from 301.15 K to 363.15 K under atmospheric pressure for the binary mixture of diethylene glycol diethyl ether+ water. Li XX, et al.J. Chem. Eng. Data 49(4) , 1043-1045, (2004)
Excess molar volumes and viscosities of binary mixtures of diethylene glycol diethyl ether with chloroalkanes at 298.15 K. Pal A and Bhardwaj RK.
J. Mol. Liq. 102(1) , 197-211, (2003)