N-Methylsuccinimide

Names

[ Name ]:
N-Methylsuccinimide

[Synonym ]:
1-Methyl-2,5-pyrrolidinedione
2,5-Pyrrolidinedione, 1-methyl-
MFCD00005517
1-Methylpyrrolidine-2,5-dione
N-Methylsuccinimide

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
234.0±0.0 °C at 760 mmHg

[ Melting Point ]:
61-70 °C(lit.)

[ Molecular Formula ]:
C₅H₇NO₂

[ Molecular Weight ]:
113.115

[ Flash Point ]:
105.9±11.1 °C

[ Exact Mass ]:
113.047676

[ PSA ]:
37.38000

[ LogP ]:
-0.95

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.493

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S26-S36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
UY1028650

[ HS Code ]:
2925190090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

nfrared Study of the Hydrogen Bond Complexes Between N-Methylsuccinimide and Phenols. Bruyneel K, et al.

Spectrosc. Lett. 29(4) , 739-47, (1996)

N-Methylsuccinimide in plasma and urine as a biomarker of exposure to N-methyl-2-pyrrolidone. Jönsson BAG and Åkesson B.

Int. Arch. Occup. Environ. Health 74(4) , 289-94, (2004)

Modeling the enolization of succinimide derivatives, a key step of racemization of aspartic acid residues: importance of a two-H2O mechanism.

Chem. Biodivers. 7(6) , 1349-56, (2010)

Racemization of aspartic acid residues in peptides and proteins is assumed to proceed via succinimide intermediates. An enolization of the succinimide intermediate is required for the racemization to ...

2-Ethyl-N-methylsuccinimide
2-Benzyl-N-methylsuccinimide
2-hydroxy-N-methylsuccinimide
3-hydroxy-N-methylsuccinimide
3-hydroxy-N-methylsuccinimide
2-(p-Iodophenyl)-N-methylsuccinimide
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
2-Methyl-4-(thiolan-3-yloxy)-6-(trifluoromethyl)pyrimidine
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
tert-Butyl 2-amino-2-(tetrahydro-2H-pyran-4-yl)acetate
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine