3-Hydroxy-2-Methylpyridine

Names

[ Name ]:
3-Hydroxy-2-Methylpyridine

[Synonym ]:
3-Hydroxy-2-methylpyridine
3-Pyridinol, 2-methyl-
EINECS 214-327-3
Pyridyl-3-methanol
2-Methyl-3-pyridinol
2-methyl-3-hydroxypyridine
2-methylpyridin-3-ol
MFCD00082538

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
287.1±20.0 °C at 760 mmHg

[ Melting Point ]:
168-169 °C(lit.)

[ Molecular Formula ]:
C₆H₇NO

[ Molecular Weight ]:
109.126

[ Flash Point ]:
127.4±21.8 °C

[ Exact Mass ]:
109.052765

[ PSA ]:
33.12000

[ LogP ]:
1.10

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.551

MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36/37/38;R41

[ Safety Phrases ]:
S26-S37/39-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

1-(Furan-2-yl)ethanone
2-picoline
(2S)-1-benzyl-2-methyl-1,6-dihydropyridin-3(2H)-one
2-(DIMETHYLAMINOMETHYL)-3-HYDROXYPYRIDINE
2-Deoxy-D-glucose
2,3-O-Isopropylidene-1,6-di-O-p-toluenesulfonyl-a-L-sorbofuranose
alpha-l-Sorbofuranose, 2,3-O-(1-methylethylidene)-
2-BROMOMETHYL-3-HYDROXYPYRIDINEHYDROBROMIDE

DownStream

2-Methyl-3-phenylpyridine
Phenyl {6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl}carbamate
3-(5-nitropyridin-2-yloxy)-2-methylpyridine
4,6-dibromo-2-methylpyridin-3-ol
6-Bromo-2-methyl-3-pyridinol
Pyridinium,3-hydroxy-1,2-dimethyl-, iodide (1:1)
3-Hydroxypicolinic acid
6-Hydroxymethyl-2-methyl-pyridin-3-ol
3-Hydroxy-2-pyridinecarbaldehyde
3-Methoxy-2-methylpyridine

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Pyridoxal phosphate decreases in plasma but not erythrocytes during systemic inflammatory response.

Clin. Chem. 49(3) , 515-8, (2003)

1-[2-[(Heteroaryloxy)heteroaryl]carbamoyl]indolines: novel and selective 5-HT2C receptor inverse agonists with potential as antidepressant/anxiolytic agents.

Bioorg. Med. Chem. Lett. 10(16) , 1863-6, (2000)

Bisaryl ethers have been identified with excellent 5-HT2C affinity and selectivity over both 5-HT2A and 5-HT2B receptors. Compounds such as 11, 27 and 38 have potent oral activity in a centrally media...

3-Hydroxy-2-Methylpyridine-d3
5-Bromo-3-hydroxy-2-methylpyridine
5-Ethyl-3-hydroxy-2-methylpyridine
6-Ethyl-3-hydroxy-2-methylpyridine
5-Cyano-3-hydroxy-2-methylpyridine
4-Cyano-3-hydroxy-2-methylpyridine
3-(2H-1,3-benzodioxol-5-yl)-1-{[4-(morpholin-4-yl)thian-4-yl]methyl}urea
3-(4-Fluorophenyl)-6-(4-{[5-(oxan-4-yl)-1,3,4-oxadiazol-2-yl]methyl}piperazin-1-yl)pyridazine
6-[3-(2-Methylbenzimidazol-1-yl)azetidin-1-yl]-[1,2,4]triazolo[4,3-b]pyridazine
N'-(2,6-dimethylphenyl)-N-{[1-(morpholin-4-yl)cyclobutyl]methyl}ethanediamide
Tert-butyl 4-[(4-oxo-3,4-dihydroquinazolin-3-yl)methyl]piperidine-1-carboxylate
tert-butyl 3-(2-methyl-1H-1,3-benzodiazol-1-yl)azetidine-1-carboxylate
2-{4-[6-(pyridin-4-yl)pyridazin-3-yl]piperazin-1-yl}-4H-pyrido[1,2-a]pyrimidin-4-one
2-[4-(6-Pyridin-2-ylpyridazin-3-yl)piperazin-1-yl]pyrido[1,2-a]pyrimidin-4-one
2-{4-[6-(pyridin-3-yl)pyridazin-3-yl]piperazin-1-yl}-4H-pyrido[1,2-a]pyrimidin-4-one
2-methyl-1-(1-{3-methyl-3H-imidazo[4,5-b]pyridin-2-yl}azetidin-3-yl)-1H-1,3-benzodiazole

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