Pyrithione

Suppliers

Names

[ CAS No. ]:
1121-31-9

[ Name ]:
Pyrithione

[Synonym ]:
2-mercaptopyridine-N-oxide
pyridine-2-thiol N-oxide
MercaptopyridineNoxide
PYRITHIONE
N-Hydroxy-2-thiopyridone
2-mercaptopyridine-1-oxide
2-pyridinethiol-1-oxide
2-thiopyridine-N-oxide
2-Mercapto pyridine oxide
2-Pyridinethiol 1-oxide
PYRIDINETHIOLOXIDE
Omadine
Pyridine-2-thiol 1-oxide
PYRIDINE-2-THIOL-1-OXIDE
1-Hydroxy-2-pyridinethione
EINECS 214-329-4
2-mercaptopyridine 1-oxide
pyridine-N-oxide-2-thiophenol
MFCD00006196
2-mercapto-pyridine N-oxide
2-mercaptopyridine n-oxide
2-Pyridinethiol, 1-oxide
2-Pyridinethiol N-oxide

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
350.2±15.0 °C at 760 mmHg

[ Melting Point ]:
70-72 °C

[ Molecular Formula ]:
C5H5NOS

[ Molecular Weight ]:
127.164

[ Flash Point ]:
165.6±20.4 °C

[ Exact Mass ]:
127.009186

[ PSA ]:
64.26000

[ LogP ]:
-0.90

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.614

[ Storage condition ]:
Refrigerator

[ Stability ]:
Stable. Incompatible with strong bases, strong oxidizing agents.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UT8999000
CHEMICAL NAME :
2-Pyridinethiol, 1-oxide
CAS REGISTRY NUMBER :
1121-31-9
LAST UPDATED :
199706
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C5-H5-N-O-S
MOLECULAR WEIGHT :
127.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
178 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 48,371,1976

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H315-H319-H335

[ Precautionary Statements ]:
P261-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ RTECS ]:
UT8999000

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Chloropyridine-N-oxide
  • 1-Propanol
  • 2-Chloropyridine-N-oxide hydrochloride
  • 2-Chloropyridine

DownStream

  • (2-sulfanylidenepyridin-1-yl) cyclohexanecarboxylate
  • 2,2'-Dithiobis(pyridine-N-oxide)
  • 1-oxa-2-oxo-3-thiaindolizinium chloride
  • 2-Pyridinethiol
  • (2-sulfanylidenepyridin-1-yl) 3-phenylpropanoate
  • Pyrithione
  • (2-sulfanylidenepyridin-1-yl) 2,2-dimethylpropanoate
  • 2-[(4-fluorophenyl)disulfanyl]-1-oxidopyridin-1-ium
  • n-propyl 2-pyridyl disulfide

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Hypoxia lowers SLC30A8/ZnT8 expression and free cytosolic Zn2+ in pancreatic beta cells.

Diabetologia 57(8) , 1635-44, (2014)

Hypoxic damage complicates islet isolation for transplantation and may contribute to beta cell failure in type 2 diabetes. Polymorphisms in the SLC30A8 gene, encoding the secretory granule zinc transp...

ELEMENTAL SELENIUM GENERATED BY THE PHOTOBLEACHING OF SELENOMEROCYANINE PHOTOSENSITIZERS FORMS CONJUGATES WITH SERUM MACROMOLECULES THAT ARE TOXIC TO TUMOR CELLS.

Phosphorus. Sulfur. Silicon Relat. Elem. 67 , 311, (1992)

Elemental selenium generated by the photobleaching of selenomerocyanine dyes forms conjugates with serum albumin and serum lipoproteins that are toxic to leukemia and selected solid tumor cells but we...

Fusaric acid induces a notochord malformation in zebrafish via copper chelation.

Biometals 28 , 783-9, (2015)

Over a thousand extracts were tested for phenotypic effects in developing zebrafish embryos to identify bioactive molecules produced by endophytic fungi. One extract isolated from Fusarium sp., a wide...


More Articles

Related Compounds

  • Pyrithione
  • PYRITHIONE
  • Zinc Pyrithione
  • pyrithione sodium
  • Sodium Pyrithione
  • COPPER PYRITHIONE
  • [[(2Z)-3,7-dimethylocta-2,6-dienylidene]amino]urea
  • 4-[1-(5-Methylpyrimidin-2-yl)piperidine-4-carbonyl]morpholine
  • 4-{1-[6-(Trifluoromethyl)pyridin-3-yl]piperidine-4-carbonyl}morpholine
  • 3-Methyl-6-[4-(thiomorpholine-4-carbonyl)piperidin-1-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • 4-[1-(5-Fluoropyrimidin-4-yl)pyrrolidine-3-carbonyl]morpholine
  • 2-[3-(4,4-Difluoropiperidine-1-carbonyl)pyrrolidin-1-yl]-5-methylpyrimidine
  • 1,3-Dimethyl-6-[3-(pyrrolidine-1-carbonyl)azetidin-1-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • N-{[1-(4,6-dimethylpyrimidin-2-yl)-4-fluoropiperidin-4-yl]methyl}acetamide
  • N-{[4-fluoro-1-(4-methylpyrimidin-2-yl)piperidin-4-yl]methyl}acetamide
  • N-{[4-fluoro-1-(5-methylpyrimidin-2-yl)piperidin-4-yl]methyl}acetamide
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.