methyl (2S)-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate

Names

[ CAS No. ]:
112196-57-3

[ Name ]:
methyl (2S)-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate

[Synonym ]:
N-[(1,1-Dimethylethoxy)carbonyl]-O-[(1,1-dimethylethyl)dimethylsilyl]-L-tyrosine Methyl Ester
O-tert-Butyldimethylsilyl-N-t-butoxycarbonyl-L-tyrosine,Methyl Ester

Chemical & Physical Properties

[ Density]:
1.033g/cm3

[ Boiling Point ]:
468.468ºC at 760 mmHg

[ Molecular Formula ]:
C21H35NO5Si

[ Molecular Weight ]:
409.59200

[ Flash Point ]:
237.121ºC

[ Exact Mass ]:
409.22800

[ PSA ]:
77.35000

[ LogP ]:
4.88380

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.486

Synthetic Route

Precursor & DownStream

Precursor

  • Boc-L-Tyrosine methyl ester
  • tert-Butyldimethylsilyl chloride
  • H-Tyr-OMe
  • L-Tyrosine

DownStream

  • boc-n-me-tyr-oh
  • methyl (2S)-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]propanoate