(S)-tert-Leucinol

Suppliers

Names

[ Name ]:
(S)-tert-Leucinol

[Synonym ]:
(R)-(−)-tert-Leucinol
(2R)-2-amino-3,3-dimethylbutan-1-ol
MFCD00192250
(R)-tert-Leucinol
(R)-2-Amino-3,3-dimethylbutan-1-ol
(2S)-2-Amino-3,3-dimethyl-1-butanol
L-t-butyl leucinol
1-Butanol, 2-amino-3,3-dimethyl-, (2S)-
H-TLE-OL
L-T-LEUCINOL
L-Tert-Leucinol
(2S)-2-Amino-3,3-dimethylbutan-1-ol
(S)-2-Amino-3,3-dimethylbutanol
L-T-BUTYLGLYCINOL
(S)-2-Amino-3,3-dimethyl butanol

Chemical & Physical Properties

[ Density]:
0.9

[ Boiling Point ]:
198.5±13.0 °C at 760 mmHg

[ Melting Point ]:
30-34ºC(lit.)

[ Molecular Formula ]:
C₆H₁₅NO

[ Molecular Weight ]:
117.189

[ Flash Point ]:
90 ºC

[ Exact Mass ]:
117.115364

[ PSA ]:
46.25000

[ LogP ]:
0.27

[ Vapour Pressure ]:
0.1±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.452

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
1325.0

[ WGK Germany ]:
3

[ Hazard Class ]:
4.1

[ HS Code ]:
2922199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

L-tert-Leucine
(S)-tBu-PHOX oxide
1-Brom-3,3-dimethylbutan-2-on
Pivaldehyde
3.3-dimethyl-2-one-butanoicacid Na Salt
H-Tle-OMe.HCl

DownStream

(S)-(-)-4-tert-Butyl-2-oxazolidinone
(S,S)-(-)-2,2'-Isopropylidenebis(4-tert-butyl-2-oxazoline)
2,2'-Methylenebis[(4S)-4-tert-butyl-2-oxazoline]
2,6-Bis[(4S)-4-tert-butyloxazolin-2-yl]pyridine
(4S)-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-4,5-dihydrooxazole
(S)-2-(2-Bromophenyl)-4-(tert-butyl)-4,5-dihydrooxazole
(S)-(-)-2-(3 5-DI-TERT-BUTYLSALICYLIDEN&
(S)-N-BOC-TERT-LEUCINOL
(4R)-4-BENZYL-D-GLUTAMICACID

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Synthesis and Properties of a Novel Pyridineoxazoline Containing Optically Active Helical Polymer as a Catalyst Ligand for Asymmetric Diels-Alder Reaction.

Chirality 27 , 523-31, (2015)

A novel pyridineoxazoline (PyOx) containing helical polymer, poly{(-)-(S)-4-tert-butyl-2-[5-(4-tert-butylphenyl)-3-vinylpyridin-2-yl]-oxazoline} (PA), was designed and synthesized to approach the effe...

SimplePHOX, a readily available chiral ligand system for iridium-catalyzed asymmetric hydrogenation.

Org. Lett. 6 , 2023-2026, (2004)

[reaction: see text] New Ir-SimplePHOX complexes Ir-6-Ir-9 catalyze the quantitative, highly enantioselective hydrogenation of a range of unfunctionalized and functionalized olefins. Synthesis, cataly...

Tetrahedron Lett. 45 , 5649, (2004)

(S)-N-BOC-TERT-LEUCINOL
(S)-TERT-BUTYL 4-BENZYL-2-METHYLPIPERAZINE-1-CARBOXYLATE
(S)-tert-butyl 3-(Methoxy(Methyl)carbamoyl)piperidine-1-carboxylate
(S)-tert-Butyl 1-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-ylcarbamate
(S)-Tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate
S-tert-butyl hexanethioate
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
3-(Piperidin-1-ylcarbonyl)-1-propyl-1H-pyrazol-4-amine
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
Caprenin
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
(S,E)-N-(3-(Difluoromethoxy)benzylidene)-2-methylpropane-2-sulfinamide