3,4-Dichloro-1-methyl-1H-pyrrole-2,5-dione

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Names

[ CAS No. ]:
1123-61-1

[ Name ]:
3,4-Dichloro-1-methyl-1H-pyrrole-2,5-dione

[Synonym ]:
Dichloro-N-methylmaleimide
N-Methyldichloromaleimide
1H-Pyrrole-2,5-dione, 3,4-dichloro-1-methyl-
2,3-Dichlor-N-methylmaleinimid
3,4-Dichloro-1-methyl-1H-pyrrole-2,5-dione
2,3-Dichloro-N-methylmaleinimide
Maleimide,dichloro-N-methyl
3,4-dichloro-N-methylmaleimide
3,4-dichloro-1-methylmaleimide
N-Methyl-3,4-dichloromaleimide
2,3,5-TRINITROTOLUENE
n-Methyl-dichloromaleinimide
N-Methyl-2,3-dichloromaleimide
2,3-Dichloro-N-methylmaleimide

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
205.7±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C5H3Cl2NO2

[ Molecular Weight ]:
179.989

[ Flash Point ]:
78.2±27.3 °C

[ Exact Mass ]:
178.954086

[ PSA ]:
37.38000

[ LogP ]:
0.71

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.576

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ON5200000
CHEMICAL NAME :
Maleimide, 2,3-dichloro-N-methyl-
CAS REGISTRY NUMBER :
1123-61-1
BEILSTEIN REFERENCE NO. :
0127988
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C5-H3-Cl2-N-O2
MOLECULAR WEIGHT :
179.99
WISWESSER LINE NOTATION :
T5VNVJ B1 DG EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 37,15,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03682 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
3100 ug/kg
SEX/DURATION :
female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - other developmental abnormalities Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 37,15,1976

Safety Information

[ HS Code ]:
2925190090

Synthetic Route

Precursor & DownStream

Precursor

  • Dichloromaleic anhydride
  • Methylamine hydrochloride
  • methylamine
  • N-Methylmaleimide

DownStream

  • n-methylbis(indol-3-yl)maleimide

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%


Related Compounds

  • 3,4-dichloro-1-[(4-chlorophenyl)methyl]pyrrole-2,5-dione
  • 3,4-dichloro-1-[(4-methoxyphenyl)methyl]pyrrole-2,5-dione
  • 3,4-Dichloro-1-(2-ethoxyphenyl)-1H-pyrrole-2,5-dione
  • 3,4-Dichloro-1-(3-(trifluoromethyl)phenyl)-1H-pyrrole-2,5-dione
  • 3,4-dichloro-1-(3,5-dichlorophenyl)-1H-pyrrole-2,5-dione
  • 3,4-dichloro-1-hexylpyrrole-2,5-dione
  • N-((1-methoxyisoquinolin-4-yl)methyl)propan-2-amine
  • 5-(5-Methoxy-2-methyl-2,3-dihydrobenzofuran-6-yl)cyclohexane-1,3-dione
  • 1-(6-Bromo-3-chloro-2-fluorophenyl)ethanol
  • 3-(2-Chloro-5-methoxyphenyl)-1,2-oxazole-5-carboxylic acid
  • 1-Amino-5-(4-bromophenyl)pentan-3-ol
  • 1-(5-Bromo-2,3-dimethoxyphenyl)cyclobutan-1-amine
  • 5-Benzyl-2-bromo-1H-imidazole
  • 6-(Ethylamino)pyrimidine-4-carbonitrile
  • 6-[(Propan-2-yl)amino]pyrimidine-4-carbonitrile
  • 4-Pyrimidinecarbonitrile, 6-[(3-methoxypropyl)amino]-
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