2,5-Dibromo-N-[(3R,5S)-1-cyano-5-methyl-3-pyrrolidinyl]benzenesul fonamide

Names

[ CAS No. ]:
1123307-53-8

[ Name ]:
2,5-Dibromo-N-[(3R,5S)-1-cyano-5-methyl-3-pyrrolidinyl]benzenesul fonamide

[Synonym ]:
2,5-Dibromo isonicotinic acid

Chemical & Physical Properties

[ Molecular Formula ]:
C12H13Br2N3O2S

[ Molecular Weight ]:
423.12400

[ Exact Mass ]:
420.91000

[ PSA ]:
81.58000

[ LogP ]:
3.84338

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Cyanogen bromide
  • 1,1-dimethylethyl (2S,4R)-4-{[(2,5-dibromophenyl)sulfonyl]amino}-2-methyl-1-pyrrolidinecarboxylate
  • 4-(tert-butyldimethylsilanyloxy)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester
  • 1,1-dimethylethyl (2S,4S)-4-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}-2-methyl-1-pyrrolidinecarboxylate
  • Boc-trans-D-Hyp-OMe
  • D-Proline, 4-hydroxy-, methyl ester, (4S)
  • L-Hydroxyproline
  • 1,1-dimethylethyl (2S,4S)-4-hydroxy-2-methyl-1-pyrrolidinecarboxylate

DownStream