[(11Z,13E)-6-[5-(5-acetyloxy-4-hydroxy-4,6-dimethyloxan-2-yl)oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-10-[5-(dimethylamino)-6-methyloxan-2-yl]oxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-4-yl] propanoate
Names
[ CAS No. ]:
112501-15-2
[ Name ]:
[(11Z,13E)-6-[5-(5-acetyloxy-4-hydroxy-4,6-dimethyloxan-2-yl)oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-10-[5-(dimethylamino)-6-methyloxan-2-yl]oxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-4-yl] propanoate
[Synonym ]:
4'-O-Acetylspiramycin C
4'-Acetylspiramycin III
Leucomycin V,9-O-(5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl)-,4(sup B)-acetate 3-propanoate,(9-(2R,5S,6R))
Chemical & Physical Properties
[ Density]:
1.2g/cm3
[ Boiling Point ]:
931.9ºC at 760mmHg
[ Molecular Formula ]:
C48H80N2O16
[ Molecular Weight ]:
941.15300
[ Flash Point ]:
517.4ºC
[ Exact Mass ]:
940.55100
[ PSA ]:
207.52000
[ LogP ]:
3.85680
[ Vapour Pressure ]:
0mmHg at 25°C
[ Index of Refraction ]:
1.536
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OH4730560
- CHEMICAL NAME :
- Leucomycin V, 9-O-(5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2- yl)-, 4(sup B)-acetate 3- propanoate, (9-(2R,5S,6R))-
- CAS REGISTRY NUMBER :
- 112501-15-2
- LAST UPDATED :
- 199303
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C48-H80-N2-O16
- MOLECULAR WEIGHT :
- 941.30
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 949 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 43,1521,1990