Pioglitazone hydrochloride

Suppliers

Names

[ CAS No. ]:
112529-15-4

[ Name ]:
Pioglitazone hydrochloride

[Synonym ]:
Effects of pioglitazone
PIODLITAZONE HYDROCHLORIC
Pioglitazonehydrochloride
Pioglitazone hydrochloride
5-{4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione hydrochloride (1:1)
MFCD04975446
Pioditazone hydrochloride
5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione hydrochloride
5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione hydrochloride
5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione hydrochloride
5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione Hydrochloride
5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione monohydrochloride
2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-, hydrochloride (1:1)
UNII:JQT35NPK6C
5-{4-[2-(5-éthylpyridin-2-yl)éthoxy]benzyl}-1,3-thiazolidine-2,4-dione chlorhydrate
5-{4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidin-2,4-dionhydrochlorid
Actos
Pioglitazone HCl
5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione hydrochloride (1:1)
Pioglitazone hydrochloride
AD-4833
Pioglitazone (hydrochloride)

Chemical & Physical Properties

[ Density]:
1.26 g/cm3

[ Boiling Point ]:
575.4ºC at 760 mmHg

[ Melting Point ]:
193-194ºC

[ Molecular Formula ]:
C19H21ClN2O3S

[ Molecular Weight ]:
392.900

[ Flash Point ]:
301.8ºC

[ Exact Mass ]:
392.096130

[ PSA ]:
93.59000

[ LogP ]:
4.29040

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.64

[ Storage condition ]:
Desiccate at RT

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/38

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione
  • 2-bromo-3-{4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}propionic acid
  • Pioglitazone 2-Imine
  • 5-Ethyl-2-pyridineethanol
  • N-(5-{4-[2-(5-ethyl-pyridin-2-yl)ethoxy]benzyl}-4-oxo-4,5-dihydrothiazol-2-yl)-4-methylbenzenesulfonamide
  • 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzylene}-2,4-thiazolidinedione
  • 5-Ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine
  • 1-Fluoro-4-nitrobenzene
  • 2-Pyridineethanol, 5-ethyl-, 1-oxide

DownStream

  • (2S,3S,4S,5R,6R)-6-[5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-2,4-dioxo-1,3-thiazolidin-3-yl]-3,4,5-trihydroxyoxane-2-carboxylic acid
  • Pioglitazone Thiazolidinedione Ring-opened N-β-D-Glucuronide
  • Pioglitazone N-Oxide

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Insulin sensitizers improve learning and attenuate tau hyperphosphorylation and neuroinflammation in 3xTg-AD mice.

J. Neural Transm. Gen. Sect. 122(4) , 593-606, (2015)

Sporadic Alzheimer's disease (AD) is a multifactorial metabolic brain disorder characterized by progressive neurodegeneration. Decreased brain energy and glucose metabolism occurs before the appearanc...

Antihyperglycemic activities of extracts of the mistletoes Plicosepalus acaciae and P. curviflorus in comparison to their solid lipid nanoparticle suspension formulations.

Z. Naturforsch., C, J. Biosci. 69(9-10) , 391-8, (2015)

The antihyperglycemic activity of the extracts and preparations of solid lipid nanoparticle suspensions of two mistletoes growing in Saudi Arabia, Plicosepalus acaciae and P. curviflorus, as well as t...

Thiazolidinediones cause compaction of nuclear heterochromatin in the pluripotent mesenchymal cell line C3H10T1/2 when inducing an adipogenic phenotype.

Anal. Quant. Cytol. Histol. 35(2) , 85-94, (2013)

To characterize the nuclear changes induced in vitro by thiazolidinediones (TZDs) in a murine pluripotent mesenchymal cell line.The C3H10T1/2 cell line, which can differentiate either in osteoblast or...


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Related Compounds

  • 1-Hydroxy Pioglitazone Hydrochloride
  • 2-Hydroxy Pioglitazone Hydrochloride
  • Pioglitazone hydrochloride and glimepiride
  • Pioglitazone hydrochloride impurity A [EP]
  • Pioglitazone hydrochloride specified impurity C [EP]
  • Pioglitazone hydrochloride and metformin hydrochloride