6-(Bromomethyl)-2-methyl-4(1H)-quinazolinone

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Names

[ CAS No. ]:
112888-43-4

[ Name ]:
6-(Bromomethyl)-2-methyl-4(1H)-quinazolinone

[Synonym ]:
MFCD06200810
6-(Bromomethyl)-2-methylquinazolin-4(1H)-one
6-Bromomethyl-3,4-dihydro-2-methyl quinazolin-4-one
6-(bromomethyl)-2-methyl-1H-quinazolin-4-one
4(3H)-Quinazolinone, 6-(bromomethyl)-2-methyl-
6-(Bromomethyl)-2-methyl-4(1H)-quinazolinone
6-(Bromomethyl)-2-methylquinazolin-4(3H)-one
4(1H)-quinazolinone, 6-(bromomethyl)-2-methyl-

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
178

[ Molecular Formula ]:
C10H9BrN2O

[ Molecular Weight ]:
253.095

[ Flash Point ]:
70.5

[ Exact Mass ]:
251.989822

[ PSA ]:
45.75000

[ LogP ]:
1.41

[ Vapour Pressure ]:
1.37E-06mmHg at 25°C

[ Index of Refraction ]:
1.670

Safety Information

[ Hazard Codes ]:
T

[ Risk Phrases ]:
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36/37/39

[ HS Code ]:
2933990090

Synthetic Route

Precursor & DownStream

Precursor

  • 4(3H)-Quinazolinone,2,6-dimethyl-
  • 2(1H)-quinazolinone
  • 3,4 dihydro-2,6 dimethylquinazolin
  • N-Bromosuccinimide
  • 2-Amino-5-methylbenzoic acid
  • 2-Acetamido-5-methylbenzoic acid
  • 2,6-DIMETHYL-4H-3,1-BENZOXAZIN-4-ONE

DownStream

  • Raltitrexed
  • Diethyl N-[5-[N-[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]-N-methylamino]-2-thenoyl]-L-glutamate
  • 4-Aminobenzoic acid
  • (2S)-2-[[4-[(2-methyl-4-oxo-1H-quinazolin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]pentanedioic acid

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 6-(Hydroxymethyl)-2-methylquinazolin-4(1H)-one
  • 6-(Dimethylamino)-2-methyl-4(1H)-quinolinone
  • 6-bromomethyl-2-methyl-5,6-dihydro-[1,3]oxazine-4,4-dicarboxylic acid diethyl ester, hydrobromide
  • 6-(broMoMethyl)-1-Methylquinazolin-4(1H)-one
  • 6-bromomethyl-3,4-dihydro-2-methyl-4-oxo-3-((pivaloyl)oxy)methylquinazoline
  • 6-(bromomethyl)-1,3-dimethyl-5-nitropyrimidine-2,4(1H,3H)-dione
  • (2S)-N-(4-hydroxybutyl)pyrrolidine-2-carboxamide
  • 5-[(4-Hydroxybutyl)amino]pyridine-2-carbonitrile
  • 3-(Cyclobutyl(methyl)amino)-1,1,1-trifluoropropan-2-ol
  • 4-[(5-Bromopyridin-2-yl)amino]butan-1-ol
  • 4-((4-Chloro-2-nitrophenyl)amino)butan-1-ol
  • 4-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]benzenemethanamine
  • (2S,4S)-4-(4-(((Benzyloxy)carbonyl)amino)-2-oxopyrimidin-1(2H)-yl)-1-(2-((tert-butoxycarbonyl)amino)ethyl)pyrrolidine-2-carboxylic acid
  • 1-[(1-Methyl-1h-pyrazol-5-yl)sulfonyl]-4-piperidinone
  • (2S,3S,4S)-1,4-Dimethyl-3-phenyl-2-azetidinemethanol
  • 2-Hydroxyethyl I-oxobenzenepentanoate
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