Ethyl 6-fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate

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Names

[ CAS No. ]:
113028-17-4

[ Name ]:
Ethyl 6-fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate

[Synonym ]:
Ethyl 6-fluoro-4-oxo-7-piperazin-1-yl-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate
ulifloxacin ethyl ester
Prulifloxacin Intermediate PL-10
Ethyl 6-fluoro-4-oxo-7-(1-piperazinyl)-1H,4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate
T B466 BN DS GV CHJ FVO2 JF K- DT6M DNTJ
1H,4H-[1,3]Thiazeto[3,2-a]quinoline-3-carboxylic acid, 6-fluoro-4-oxo-7-(1-piperazinyl)-, ethyl ester
Ethyl 6-fluoro-4-oxo-7-(1-piperazinyl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate
PRULIFLOXACIN INTERMEDIATE 2
MFCD08063938

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
581.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H20FN3O3S

[ Molecular Weight ]:
363.406

[ Flash Point ]:
305.2±30.1 °C

[ Exact Mass ]:
363.105286

[ PSA ]:
88.87000

[ LogP ]:
1.87

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.679

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Piperazine
  • Ethyl 6,7-difluoro-1-methyl-4-oxo-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate
  • 3,4-Difluorophenyl isothiocyanate
  • triethylammonium (3,4-difluorophenyl)dithiocarbamate
  • 3,4-Difluoroaniline
  • 6,7-Difluoro-4-hydroxy-2-mercaptoquinoline-3-carboxylicacidethylester
  • ethyl 6,7-difluoro-4-hydroxy-2-[(methoxymethyl)thio]-quinoline-3-carboxylate
  • diethyl[[(3,4-difluorophenyl)amino][(methoxymethyl)-thio]methylene]malonate

DownStream

  • UNII:C38638H76Y
  • Prulifloxacin

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%