2-Amino-2-methyl-3-phenylpropionic acid

Names

[ CAS No. ]:
1132-26-9

[ Name ]:
2-Amino-2-methyl-3-phenylpropionic acid

[Synonym ]:
MFCD00010512
2-amino-2-methyl-3-phenylpropanoic acid

Chemical & Physical Properties

[ Density]:
1.158 g/cm3

[ Boiling Point ]:
306ºC at 760 mmHg

[ Melting Point ]:
293-294ºC (dec.)

[ Molecular Formula ]:
C₁₀H₁₃NO₂

[ Molecular Weight ]:
179.21600

[ Flash Point ]:
138.9ºC

[ Exact Mass ]:
179.09500

[ PSA ]:
63.32000

[ LogP ]:
1.73140

[ Vapour Pressure ]:
0.000345mmHg at 25°C

[ Index of Refraction ]:
1.561

[ Storage condition ]:
Store at RT.

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Benzyl bromide
(+/-)-N-(tert-butoxycarbonyl)-α-methylphenylalanine
POTASSIUM CYANIDE
Phenylacetone
Benzyl chloride
METHYL 2-([(E)-PHENYLMETHYLIDENE]AMINO)PROPANOATE
ethyl 2-(diphenylmethyleneamino)propanoate
rac-4-benzyl-4-methyl-2-phenyl-1,3-oxazol-5(4H)-one

DownStream

a-methyl-D-phenylalanine
a-methyl-L-phenylalanine
Benzeneethanamine, a-methyl-
Phenylacetone
ethyl alpha-methylphenylalaninate
BOC-ALPHA-METHYL-D-PHE
ALPHA-METHYL-DL-PHENYLALANINE METHYL ESTER HYDROCHLORIDE

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

Nat. Chem. Biol. 5 , 45-52, (2009)

Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting tr...

Effects of dietary mixtures of amino acids on fetal growth and maternal and fetal amino acid pools in experimental maternal phenylketonuria.

Am. J. Clin. Nutr. 69(4) , 687-96, (1999)

Branched-chain amino acids have been reported to improve fetal brain development in a rat model in which maternal phenylketonuria (PKU) is induced by the inclusion of an inhibitor of phenylalanine hyd...

Inhibition of brain and liver 3-hydroxy-3-methylglutaryl-CoA reductase and mevalonate-5-pyrophosphate decarboxylase in experimental hyperphenylalaninemia.

Neurochem. Res. 13(6) , 551-5, (1988)

Experimental hyperphenylalaninemia has been induced in 5-day-old chicks by dietary treatments with phenylalanine and alpha-methylphenylalanine. An increase of nearly 8-fold in plasma Phe/Tyr ratio was...

(S)-2-Amino-2-methyl-3-phenylpropionic acid
(R )-2-Amino-2-methyl-3-phenylpropionic acid
2-amino-2-methyl-3-methoxy-propanoic acid
2-amino-2-methyl-3-methylamino-propanoic acid
2-AMINO-2-METHYL-3-HYDROXY-PROPANOIC ACID ETHYL ESTER
(2S)-2-amino-2-methyl-3-sulfanylbutanoic acid
3-(Difluoromethyl)-2-fluoro-5-nitropyridin-4-amine
2-(4,5-Dibromo-2-(difluoromethyl)pyridin-3-yl)acetonitrile
2-(4,5-Dibromo-3-(difluoromethyl)pyridin-2-yl)acetonitrile
4-Amino-2-(difluoromethyl)-6-(trifluoromethyl)nicotinonitrile
4,5-Dichloro-2-(difluoromethoxy)anisole
2-(4-Amino-5-(difluoromethyl)-6-methylpyridin-2-yl)acetonitrile
2-(4-Amino-3-(difluoromethyl)-5-hydroxypyridin-2-yl)acetonitrile
6-(Aminomethyl)-3-(difluoromethyl)-2-(trifluoromethoxy)pyridin-4-amine
4-Amino-5-(difluoromethyl)-3-(hydroxymethyl)pyridin-2-ol
2-(4-Amino-5-(difluoromethyl)-3-methylpyridin-2-yl)acetic acid

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