ethyl 9',10'-difluoro-7'-oxospiro[cyclopropane-1,3'(2'H)-[7H]pyrido[1,2,3-de][1,4]benzoxazine]-6'-carboxylate

Names

[ CAS No. ]:
113211-51-1

[ Name ]:
ethyl 9',10'-difluoro-7'-oxospiro[cyclopropane-1,3'(2'H)-[7H]pyrido[1,2,3-de][1,4]benzoxazine]-6'-carboxylate

[Synonym ]:
ethyl 9,10-difluoro-7-oxo-2,7-dihydrospiro[[1,4]oxazino[2,3,4-ij]quinoline-3,1'-cyclopropane]-6-carboxylate
.ethyl 9',10'-difluoro-7'-oxospiro[cyclopropane-1,3'(2'H)-[7H]pyrido(1,2,3-de)[1,4]benzoxazine]-6'-carboxylate

Chemical & Physical Properties

[ Molecular Formula ]:
C16H13F2NO4

[ Molecular Weight ]:
321.27600

[ Exact Mass ]:
321.08100

[ PSA ]:
57.53000

[ LogP ]:
2.33790

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ethyl 2,3,4,5-tetrafluoro-α-[[[1-(hydroxymethyl)cyclopropyl]amino]methylene]-β-oxobenzenepropanoate

DownStream

  • 9'-fluoro-10'-(4-methyl-1-piperazinyl)-7'-oxospiro(cyclopropane-1,3'(2'H)-(7H)pyrido(1,2,3-de)(1,4)benzoxazine)-6'-carboxylic acid

Related Compounds

  • N-(2,5-dimethylphenyl)-2-(2-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-5-methoxy-4-oxopyridin-1(4H)-yl)acetamide
  • N-(2,5-dimethylphenyl)-2-(5-methoxy-4-oxo-2-((4-phenylpiperazin-1-yl)methyl)pyridin-1(4H)-yl)acetamide
  • N-(2,5-dimethylphenyl)-2-(5-methoxy-2-{[(4-methylpyrimidin-2-yl)sulfanyl]methyl}-4-oxo-1,4-dihydropyridin-1-yl)acetamide
  • 2-(9-fluoro-4-oxo[1]benzothieno[3,2-d]pyrimidin-3(4H)-yl)-N-(2-methoxy-5-methylphenyl)acetamide
  • N-(4-{[(2-methoxy-4-methylphenyl)carbamoyl]methyl}-1,3-thiazol-2-yl)cyclopropanecarboxamide
  • 2-(4-((2-methoxy-5-methylphenyl)sulfonyl)piperazin-1-yl)-N,N,6-trimethylpyrimidin-4-amine
  • 2-[4-(2,5-dimethylbenzenesulfonyl)piperazin-1-yl]-N-(4-methoxyphenyl)-6-methylpyrimidin-4-amine
  • 2-(4-((2-methoxy-5-methylphenyl)sulfonyl)piperazin-1-yl)-N-(4-methoxyphenyl)-6-methylpyrimidin-4-amine
  • N-(2-(2-(3-fluorophenyl)thiazolo[3,2-b][1,2,4]triazol-6-yl)ethyl)-2-methoxy-5-methylbenzenesulfonamide
  • 2-methoxy-5-methyl-N-(4-((4-methyl-6-(pyrrolidin-1-yl)pyrimidin-2-yl)amino)phenyl)benzenesulfonamide
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