Acetyl-Hirudin (55-65) (desulfated)

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Names

[ Name ]:
Acetyl-Hirudin (55-65) (desulfated)

[Synonym ]:
ACETYL-HIRUDIN (55-65) (DESULFATED)
N-acetyl-hirudin fragment 55-65
ACETYL-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR-LEU-GLN
AC-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR-LEU-GLN-OH
ac-hirudin fragment 55-65 non-sulfated
N-ACETYL-HIRUDIN AC-FRAGMENT 55-65 NON-SULFATED
AC-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR-LEU-GLN

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₆H₉₂N₁₂O₂₅

[ Molecular Weight ]:
1453.50000

[ Exact Mass ]:
1452.63000

[ PSA ]:
598.43000

[ LogP ]:
1.95970

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Lepirudin blunts endotoxin-induced coagulation activation.

Blood 95 , 1729-1734, (2000)

During sepsis, lipopolysaccharide (LPS) triggers the development of disseminated intravascular coagulation (DIC) via the tissue factor-dependent pathway of coagulation resulting in massive thrombin ge...

Thrombin-dependent MMP-2 activity is regulated by heparan sulfate.

J. Biol. Chem. 285 , 41270-41279, (2010)

Like most metalloproteases, matrix metalloprotease 2 (MMP-2) is synthesized as a zymogen. MMP-2 propeptide plays a role in inhibition of catalytic activity through a cysteine-zinc ion pairing, disrupt...

Chemical compensation in macromolecular bridge-binding to thrombin.

Biochemistry 32 , 2947-2953, (1993)

The binding energetics of eight synthetic peptides capable of interfering with thrombin function have been studied by steady-state measurements and clotting assays. The synthetic peptides are bifuncti...

Acetyl-Hirudin (55-65) (sulfated)
Hirudin (55-65) (sulfated)
Acetyl-Hirudin (54-65) (sulfated)
Acetyl-Hirudin (53-65) (sulfated)
Hirudin (54-65) (desulfated) trifluoroacetate salt
[acetyl(naphthalen-2-yl)amino] acetate
5-Bromo-6-[(pent-4-yn-2-yl)amino]pyridine-3-carboxylic acid
5-Chloro-2-[(prop-2-yn-1-yloxy)amino]pyridine-3-carboxylic acid
Ethyl 2-[(but-3-yn-1-yl)(methyl)amino]-1,3-thiazole-4-carboxylate
4-[(1-Hydroxybut-3-yn-2-yl)amino]-2-methylpyrimidine-5-carboxylic acid
4-Bromo-5-[(prop-2-en-1-yl)(prop-2-yn-1-yl)amino]furan-2-carboxylic acid
3-Methyl-1-[5-(2-methyl-1,3-dioxolan-2-yl)-1,3-thiazol-2-yl]butan-1-one
2-Methoxy-1-[5-(2-methyl-1,3-dioxolan-2-yl)-1,3-thiazol-2-yl]ethan-1-one
2-Methoxy-1-[5-(2-methyl-1,3-dioxolan-2-yl)-1,3-thiazol-2-yl]propan-1-one
4-(2-Methyl-1,3-dioxolan-2-yl)-2-(1-methylcyclopropanecarbonyl)-1,3-thiazole
1-[5-(2-Aminoethyl)-4-methyl-1,3-thiazol-2-yl]pentan-1-one

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