4,4'-Dimethyl-2,2'-bipyridine

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Names

[ Name ]:
4,4'-Dimethyl-2,2'-bipyridine

[Synonym ]:
EINECS 214-483-2
MFCD00006441
4,4'-Dimethyl-2,2'-bipyridine
T6NJ D1 B- BT6NJ D1
4,4‘-Dimethyl-2,2‘-bipyridyl
2,2'-Bipyridine, 4,4'-dimethyl-
4,4′-Dimethyl-2,2′-bipyridine
2,2'-Bi-4-picoline
2,2'-Di-4-picolyl
4,4’-Dimethyl-2,2‘-dipyridyl
4-methyl-2-(4-methylpyridin-2-yl)pyridine
4,4'-Dimethyl-2,2'-dipyridyl

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
309.3±37.0 °C at 760 mmHg

[ Melting Point ]:
169-174 °C(lit.)

[ Molecular Formula ]:
C₁₂H₁₂N₂

[ Molecular Weight ]:
184.24

[ Flash Point ]:
116.8±18.1 °C

[ Exact Mass ]:
184.100052

[ PSA ]:
25.78000

[ LogP ]:
2.20

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.566

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DW1765000

CHEMICAL NAME :: 2,2'-Bipyridine, 4,4'-dimethyl-

CAS REGISTRY NUMBER :: 1134-35-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H12-N2

MOLECULAR WEIGHT :: 184.26

WISWESSER LINE NOTATION :: T6NJ D1 B- BT6NJ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 78700 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 23,815,1985

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DW1765000

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-Bromo-4-methylpyridine
4-Picoline
1-(4-Methyl-2-pyridinyl)ethanone
2-Bromo-6-methylpyridine
2-Bromopyridine
4-Methyl-2-(tributylstannyl)pyridine
2-Bromo-5-picoline
Aminopicoline
2-Chloro-4-picoline

DownStream

4'-Methyl-2,2'-bipyridine-4-carbaldehyde
4'-Methyl-2,2'-bipyridine-4-carboxylic acid
2-[4-(3-bromopropyl)pyridin-2-yl]-4-methylpyridine
2-[4-[2-(2,5-dimethoxyphenyl)ethenyl]pyridin-2-yl]-4-methylpyridine
4-(4-chlorobutyl)-2-[4-(4-chlorobutyl)pyridin-2-yl]pyridine
trimethyl-[[2-[4-(trimethylsilylmethyl)pyridin-2-yl]pyridin-4-yl]methyl]silane
4-methyl-2-(4-methyl-6-phenylpyridin-2-yl)-6-phenylpyridine
2,2'-Bipyridine-4,4'-dicarboxaldehyde
(4'-Methyl-2,2'-bipyridin-4-yl)methanol
4-(BROMOMETHYL)-4'-METHYL-2,2'-BIPYRIDINE

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

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We present a new class of phosphorescent cyclometalated iridium(III) bipyridyl-phenylenediamine complexes [Ir(N^C)2 (bpy-DA)](PF6 ) (bpy-DA=4-(N-(2-amino-5-methoxyphenyl)aminomethyl)-4'-methyl-2,2'-bi...

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Bioorthogonal Labeling, Bioimaging, and Photocytotoxicity Studies of Phosphorescent Ruthenium(II) Polypyridine Dibenzocyclooctyne Complexes.

Chemistry 21 , 10729-40, (2015)

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