EPOETIN ALFA

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Names

[ CAS No. ]:
113427-24-0

[ Name ]:
EPOETIN ALFA

[Synonym ]:
Epoetine alfa
alphaEpoetin
Abseamed
Rhepo
Epoetina alfa
Drg-0062

Chemical & Physical Properties

[ Molecular Formula ]:
C42H73NO16

[ Molecular Weight ]:
848.02600

[ Exact Mass ]:
847.49300

[ PSA ]:
235.76000

[ LogP ]:
0.91010

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KF5887500
CHEMICAL NAME :
1-165-Erythropoietin (human clone lambda HEPOFL13 protein moiety), glycoform alpha
CAS REGISTRY NUMBER :
113427-24-0
LAST UPDATED :
199506

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20 ku/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 21,319,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20 ku/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 21,319,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20 ku/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 21,319,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
20 ku/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 21,319,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
20 ku/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 21,319,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1270 ku/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 21,319,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
20 ku/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 21,319,1990

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

  • darbepoetin alfa
  • Epoetin delta
  • Epoetin zeta
  • 20-alfa-Dhydrodydrogesterone
  • Bifikafusp alfa
  • interferon alfa-2b
  • 3-[Ethyl(methyl)amino]-4-(propan-2-yl)cyclohexan-1-ol
  • 2-{[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,3-dimethylbutanamido]methyl}-1,3-thiazole-4-carboxylic acid
  • 4-(propan-2-yl)-3-(1H-1,2,3-triazol-1-yl)cyclohexan-1-ol
  • Acetic acid, [oxybis(3-hydroxy-p-phenylene)]di-, dimethyl ester
  • 3-(1H-imidazol-1-yl)-4,4-dimethylcyclohexan-1-ol
  • 4,4-dimethyl-3-(3-methyl-1H-pyrazol-1-yl)cyclohexan-1-ol
  • 3-(5-Hydroxy-2,2-dimethylcyclohexyl)-1,3-oxazolidin-2-one
  • 3-[Ethyl(methyl)amino]-4,4-dimethylcyclohexan-1-ol
  • 4,4-Dimethyl-3-(2-methylpyrrolidin-1-yl)cyclohexan-1-ol
  • (2R)-1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2,2-dimethylbutanoyl]-4,4-difluoropyrrolidine-2-carboxylic acid
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